To describe how the given compound can be prepared using acetoacetic ester synthesis Concept introduction: Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below, Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis) Steps involved in acetoacetic ester synthesis are, Deprotonation of α carbon in acetoacetic ester Alkylation of enolate Hydrolysis of ester using aqueous acid Decarboxylation at high temperature

Question

Want to see the full answer?

Answer 1

Question

Chapter 21.5, Problem 33PTS

(a)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

(b)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

(c)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

(d)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

> You are trying to decide if there is a single reagent you can add that will make the following synthesis possible without any other major side products: 1. ☑ CI 2. H3O+ O Draw the missing reagent X you think will make this synthesis work in the drawing area below. If there is no reagent that will make your desired product in good yield or without complications, just check the box under the drawing area and leave it blank. Click and drag to start drawing a structure. Explanation Check ? DO 18 Ar B © 2025 McGraw Hill LLC. All Rights Reserved. Terms of Use | Privacy Center | Accessibility

Don't use ai to answer I will report you answer

Consider a solution of 0.00304 moles of 4-nitrobenzoic acid (pKa = 3.442) dissolved in 25 mL water and titrated with 0.0991 M NaOH. Calculate the pH at the equivalence point

Answer 2

Question

Chapter 21.5, Problem 33PTS

(a)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

(b)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

(c)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

(d)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 21.5, Problem 33PTS

(a)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

(b)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

(c)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

(d)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 21.5, Problem 33PTS

(a)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

(b)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

(c)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

(d)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 21.5, Problem 33PTS

(a)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

(b)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

(c)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

(d)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

Answer 6

Chapter 21.5, Problem 33PTS

(a)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

Answer 7

Chapter 21.5, Problem 33PTS

(a)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

Answer 8

(b)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

Answer 9

(b)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

Answer 10

(c)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

Answer 11

(c)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

Answer 12

(d)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

Answer 13

(d)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using acetoacetic ester synthesis

Concept introduction:

Acetoacetic ester synthesis is a process in which an halide is converted to a methyl ketone with two new carbon atoms (comes from acetoacetic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for acetoacetic ester synthesis a cyclic product is expected. (intramolecular acetoacetic ester synthesis)

Steps involved in acetoacetic ester synthesis are,

Deprotonation of α carbon in acetoacetic ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

Answer 14

Expert Solution & Answer

Answer 15

Expert Solution & Answer

Answer 16

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 17

Ch. 21.1 - Prob. 1CC Ch. 21.1 - Prob. 2CC Ch. 21.1 - Prob. 3CC Ch. 21.1 - Prob. 1LTS Ch. 21.1 - Prob. 4PTS Ch. 21.1 - Prob. 5ATS Ch. 21.1 - Prob. 6CC Ch. 21.1 - Prob. 7CC Ch. 21.2 - Prob. 8CC Ch. 21.2 - Prob. 9CC

Want to see the full answer?

Chapter 21 Solutions