Campbell Biology 11th Edition - Valuepack
Campbell Biology 11th Edition - Valuepack
11th Edition
ISBN: 9780134833545
Author: Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece Neil A. Campbell Lisa A. Urry
Publisher: PEARSON
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Chapter 21.5, Problem 2CC

Explain how multiple exons might have arisen in the ancestral EGF and fibronectin genes shown on the left side of Figure 21.16.

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In a disorder called gyrate atrophy, cells in the retina begin to degenerate in late adolescence, causing night blindness that progresses to total blindness.  The cause is a mutation in the gene that encodes an enzyme, ornithine aminotransferase (OAT).  Researchers sequenced the OAT gene for 5 patients with the following results: Patient A:  A change in codon 209 of UAU to UAA Patient B:  A change in codon 299 of UAC to UAG Patient C:  A change in codon 426 of CGA to UGA Patient D:  A two-nucleotide deletion at codons 64 and 65 that results in a UGA codon at position 79. Patient E:  Exon 6, including 1071 nucleotides is entirely deleted. Which patient(s) have a frameshift mutation? How many amino acids is patient E missing? Which patient(s) will produce a shortened protein?
In the module, you have learned about P-element mediated transgenesis in Drosophila and the concept of using transgenes to rescue mutant phenotypes. In the figure below, you will see a wild type fly with its natural eye colour and three mutants with their eye colours changed to vermillion, white and rosy, respectively. A schematic of P-element mediated transgenesis (as shown in the lectures) is also included in the figure. Please inspect the schematic carefully and choose which of the following statements is true:    I. Injection of the white experimental transgene into the vermillion mutant embryo will not change the vermillion mutant phenotype   II. Injection of the white experimental transgene in the rosy mutant embryo will change rosy eye colour to red (wild type)   III. Injection of the white experimental transgene in the white mutant embryo will not change the white mutant phenotype   IV. Injection of the white experimental transgene in the rosy mutant…

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Campbell Biology 11th Edition - Valuepack

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