The effect on the Grignard reagent in the reaction of one equivalent of methylmagnesium iodide with ethyl acetoacetate is to be explained and the location of deuterium in the recovered ethyl acetoacetate is to be identified. Concept introduction: Grignard reagents react with ketones and aldehydes to form alcohols. These reactions are nucleophilic addition reactions. The Grignard reagent adds to the carbonyl group of aldehydes and ketones due to electronegativity difference between carbon and oxygen. A molecule that consists of a ketone group on the β- carbon atom of an ester is generally known as β- keto ester. It contains an active methylene group between two carbonyl groups in its structure. Diethyl malonate and ethyl acetoacetate are some examples of β- keto ester.

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Answer 1

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Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 21, Problem 34P

Interpretation Introduction

Interpretation:

The effect on the Grignard reagent in the reaction of one equivalent of methylmagnesium iodide with ethyl acetoacetate is to be explained and the location of deuterium in the recovered ethyl acetoacetate is to be identified.

Concept introduction:

Grignard reagents react with ketones and aldehydes to form alcohols. These reactions are nucleophilic addition reactions.

The Grignard reagent adds to the carbonyl group of aldehydes and ketones due to electronegativity difference between carbon and oxygen.

A molecule that consists of a ketone group on the β- carbon atom of an ester is generally known as β- keto ester. It contains an active methylene group between two carbonyl groups in its structure.

Diethyl malonate and ethyl acetoacetate are some examples of β- keto ester.

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Answer 2

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Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 21, Problem 34P

Interpretation Introduction

Interpretation:

The effect on the Grignard reagent in the reaction of one equivalent of methylmagnesium iodide with ethyl acetoacetate is to be explained and the location of deuterium in the recovered ethyl acetoacetate is to be identified.

Concept introduction:

Grignard reagents react with ketones and aldehydes to form alcohols. These reactions are nucleophilic addition reactions.

The Grignard reagent adds to the carbonyl group of aldehydes and ketones due to electronegativity difference between carbon and oxygen.

A molecule that consists of a ketone group on the β- carbon atom of an ester is generally known as β- keto ester. It contains an active methylene group between two carbonyl groups in its structure.

Diethyl malonate and ethyl acetoacetate are some examples of β- keto ester.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 21, Problem 34P

Interpretation Introduction

Interpretation:

The effect on the Grignard reagent in the reaction of one equivalent of methylmagnesium iodide with ethyl acetoacetate is to be explained and the location of deuterium in the recovered ethyl acetoacetate is to be identified.

Concept introduction:

Grignard reagents react with ketones and aldehydes to form alcohols. These reactions are nucleophilic addition reactions.

The Grignard reagent adds to the carbonyl group of aldehydes and ketones due to electronegativity difference between carbon and oxygen.

A molecule that consists of a ketone group on the β- carbon atom of an ester is generally known as β- keto ester. It contains an active methylene group between two carbonyl groups in its structure.

Diethyl malonate and ethyl acetoacetate are some examples of β- keto ester.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 21, Problem 34P

Interpretation Introduction