Concepts of Genetics (11th Edition)
11th Edition
ISBN: 9780321948915
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 21, Problem 2NST
Annotation of a proteome attempts to relate each protein to a function in time and space. Traditionally, protein annotation depended on an amino acid sequence comparison between a query protein and a protein with known function. If the two proteins shared a considerable portion of their sequence, the query would be assumed to share the function of the annotated protein. Following is a representation of this method of protein annotation involving a query sequence and three different human proteins. Note that the query sequence aligns to common domains within the three other proteins. What argument might you present to suggest that the function of the query is not related to the function of the other three proteins?
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Chapter 21 Solutions
Concepts of Genetics (11th Edition)
Ch. 21 - In a sequence encompassing 99.4 percent of the...Ch. 21 - Annotation of a proteome attempts to relate each...Ch. 21 - Because of its accessibility and biological...Ch. 21 - Prob. 1CSCh. 21 - Prob. 2CSCh. 21 - Prob. 3CSCh. 21 - HOW DO WE KNOW? In this chapter, we focused on the...Ch. 21 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 21 - What is functional genomics? How does it differ...Ch. 21 - Compare and contrast WGS to a map-based cloning...
Ch. 21 - What is bioinformatics, and why is this discipline...Ch. 21 - Describe three major goals of the Human Genome...Ch. 21 - Prob. 7PDQCh. 21 - BLAST searches and related applications are...Ch. 21 - Prob. 9PDQCh. 21 - Describe the human genome in terms of genome size,...Ch. 21 - What functional information about a genome can be...Ch. 21 - The Human Genome Project has demonstrated that in...Ch. 21 - Annotation involves identifying genes and...Ch. 21 - Through the Human Genome Project (HGP), a...Ch. 21 - Describe the significance of the Genome 10K...Ch. 21 - Prob. 16PDQCh. 21 - Prob. 17PDQCh. 21 - What are DNA microarrays? How are they used?Ch. 21 - Prob. 19PDQCh. 21 - Prob. 20PDQCh. 21 - Prob. 21ESPCh. 21 - Prob. 22ESPCh. 21 - Prob. 23ESPCh. 21 - Homology can be defined as the presence of common...Ch. 21 - Prob. 25ESPCh. 21 - Prob. 26ESPCh. 21 - Prob. 27ESPCh. 21 - Whole-exome sequencing (WES) is helping physicians...
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