ANATOMY AND PHYSIOLOGY
17th Edition
ISBN: 9781630180928
Author: OpenStax
Publisher: OPENSTAX C
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Textbook Question
Chapter 21, Problem 29RQ
Which type of hypersensitivity involves soluble antigen-antibody complexes?
- type I
- type II
- type III
- type IV
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Kinetics: One-Compartment First-Order Absorption
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration.
Using this data and set of graphs, determine:(calculate for each variable)
(a) k, C0, V, and AUC* for the bolus iv data
(b) k, ka, B1, and AUC* for the po data
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(e)absolute ip bioavailability, Fip
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3. A promising new drug is being evaluated in human trials. Based on preliminary human tests, this drug is most effective when plasma levels exceed 30 mg/L. Measurements from preliminary tests indicate the following human pharmacokinetic parameter values: t1/2,elim = 4.6hr, t1/2,abs = 0.34hr, VD = 0.29 L/kg, Foral = 72%. Based on these parameters, estimate the following if a 49 kg woman were to receive a 1000mg oral dose of this drug:
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(b) Estimate the time for maximum plasma concentration (tmax).
(c) Estimate the maximum plasma concentration (Cmax).
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(e)…
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Chapter 21 Solutions
ANATOMY AND PHYSIOLOGY
Ch. 21 - Visit this website...Ch. 21 - Visit this website...Ch. 21 - Visit this website...Ch. 21 - Immunity can be acquired in an active or passive...Ch. 21 - Which of the following cells is phagocytic? plasma...Ch. 21 - Which structure allows lymph from the lower right...Ch. 21 - Which of the following cells is important hi the...Ch. 21 - Which of the following cells would be most active...Ch. 21 - Which of the lymphoid nodules is most likely to...Ch. 21 - Which of the following signs is not characteristic...
Ch. 21 - Which of the following is not important in the...Ch. 21 - Enhanced phagocytosis of a cell by the binding of...Ch. 21 - Which of the following leads to the redness of...Ch. 21 - T cells that secrete cytokines that help antibody...Ch. 21 - The taking in of antigen and digesting it for...Ch. 21 - Why is clonal expansion so important? to select...Ch. 21 - The elimination of self-reactive thymocytes is...Ch. 21 - Which type of T cell is most effective against...Ch. 21 - Removing functionality from a B cell without...Ch. 21 - Which class of antibody crosses the placenta in...Ch. 21 - Which class of antibody has no known function...Ch. 21 - When does class switching occur? primary response...Ch. 21 - Which class of antibody is found in mucus? IgM IgA...Ch. 21 - Which enzymes in macrophages are important for...Ch. 21 - What type of chronic lung disease is caused by a...Ch. 21 - Which type of immune response is most directly...Ch. 21 - What is the reason that you have to be immunized...Ch. 21 - Which type of immune response works in conceit...Ch. 21 - Which type of hypersensitivity involves soluble...Ch. 21 - What causes the delay in delayed hypersensitivity?...Ch. 21 - Which of the following is a critical feature of...Ch. 21 - Which of the following is an autoimmune disease of...Ch. 21 - What drug is used to counteract the effects of...Ch. 21 - Which of the following terms means many genes?...Ch. 21 - Why do we have natural antibodies? We dont know...Ch. 21 - Which type of cancer is associated with HIV...Ch. 21 - How does cyclosporine A work? suppresses...Ch. 21 - What disease is associated with bone marrow...Ch. 21 - Describe the flow of lymph from its origins in...Ch. 21 - Describe the process of inflammation in an area...Ch. 21 - Describe two early induced responses and what...Ch. 21 - Describe the processing and presentation of an...Ch. 21 - Describe clonal selection and expansion.Ch. 21 - Describe how secondary B cell responses are...Ch. 21 - Describe the role of IgM in immunity.Ch. 21 - Describe how seroconversion works in HIV disease.Ch. 21 - Describe tuberculosis and the innocent bystander...Ch. 21 - Describe anaphylactic shock in someone sensitive...Ch. 21 - Describe rheumatic fever and how Tolerance is...Ch. 21 - Describe how stress affects immune responses.
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