Chapter 21, Problem 21.53SP

Interpretation Introduction

Interpretation:

The synthesis of given drugs are to be stated.

Concept introduction:

The Gattermann-Koch reaction is used to produce aromatic aldehydes. An aldehyde is converted into carboxylic acid with the use chromic acid reagent. An alcohol is converted into an ester through acetylation reaction.

The nitration of aromatic compounds is facilitated by ${\text{HNO}}_{\text{3}}/{\text{H}}_{\text{2}}{\text{SO}}_{\text{4}}$. The reduction of nitro group into amine group is facilitated through $\text{Fe}/\text{HCl}$. An equivalent amount of ${\text{Ac}}_{\text{2}}\text{O}$ converts amine into an amide.