Essential Organic Chemistry (3rd Edition)
3rd Edition
ISBN: 9780321937711
Author: Paula Yurkanis Bruice
Publisher: PEARSON
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Textbook Question
Chapter 21, Problem 18P
What is the sequence of bases in the sense strand of DNA that codes for the mRNA in Problem 16?
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If the nucleotide sequence of a mRNA strand is "CAU-UGA", what is the correct nucleotide
sequence that would be found on the original DNA (template) strand?
O GTA-ACT
O GUA-ACU
O ACG-GTC
O ATC-CAG
Before the mRNA transcribed from a gene can be used for translation into a protein, it must be
"Unlike what happens in DNA replication, where both strands
are copied, only one of the two strands is transcribed into
mRNA. The DNA strand that contains the gene is sometimes
called the sense strand, or coding strand, and the DNA strand
that gets transcribed to give RNA is called the antisense strand,
or noncoding strand. Because the sense strand and the antisense
strand are complementary, and because the DNA antisense
strand and the newly formed RNA strand are also
complementary, the RNA molecule produced during
transcription is a copy of the DNA sense strand... The only
difference is that the RNA molecule has a U everywhere the
DNA sense strand has a T."
Consider the following segment of a DNA sense strand:
(5') CAA-ACT-ACG-GCG-TTG-CAG (3')
(a) Determine the base sequence in the antisense (non-coding)
strand. Be sure to specify which end is 5' and which is 3'.
(b) Determine the base sequence in the messenger RNA
strand. Be sure to specify which end is 5' and which is 3'.
Chapter 21 Solutions
Essential Organic Chemistry (3rd Edition)
Ch. 21.1 - Draw the structure for each of the following: a....Ch. 21.3 - If one of the strands of DNA has the following...Ch. 21.4 - The 2,3-cyclic phosphodiester that is formed...Ch. 21.5 - Using a dark line for the original parental DNA...Ch. 21.7 - Why do both thymine and uracil specify the...Ch. 21.9 - If methionine is always the first amino acid...Ch. 21.9 - Four Cs occur in a row in the segment of mRNA...Ch. 21.9 - UAA is a stop codon. Why does the UAA sequence in...Ch. 21.9 - A change in which base of a codon would be least...Ch. 21.9 - Write the sequences of bases in the sense strand...
Ch. 21.9 - List the possible codons on mRNA that specify each...Ch. 21.10 - Adenine can be deaminated to hypoxanthine, and...Ch. 21.10 - Explain why thymine cannot be deaminated.Ch. 21.12 - Which of the following base sequences would most...Ch. 21 - Draw structures for the following: a....Ch. 21 - What nonapeptide is coded for by the following...Ch. 21 - What is the sequence of bases in the template...Ch. 21 - What is the sequence of bases in the sense strand...Ch. 21 - What would be the C-terminal amino acid if the...Ch. 21 - What would be the base sequence of the segment of...Ch. 21 - Propose a mechanism for the following reaction:Ch. 21 - A segment of DNA has 18 base pairs. It has 7...Ch. 21 - Match the codon with the anticodon: Codon: AAA GCA...Ch. 21 - Using the single-letter abbreviations for the...Ch. 21 - Indicate whether each functional group of the five...Ch. 21 - Using the A and D designations in Problem 25,...Ch. 21 - Which of the following pairs of dinucleotides are...Ch. 21 - If an mRNA contained only U and G in random...Ch. 21 - Why is the codon a triplet rather than a doublet...Ch. 21 - Human immunodeficiency virus (HIV) is the...Ch. 21 - The amino acid sequences of peptide fragments...Ch. 21 - Which cytosine in the following sense strand of...Ch. 21 - Prob. 33PCh. 21 - Why does DNA not unravel completely before...Ch. 21 - The first amino acid incorporated into a...
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- 3. Which amino acid is selected by the mRNA codon GAA? alanine glutamic acid histidine tyrosinearrow_forwardConsider the following mRNA base sequence 5ACCCAC3 a. What dipeptide is coded for by this mRNA? b. What dipeptide is formed if a point mutation converts CAC to AAC? c. What dipeptide is formed if a point mutation converts ACC to ACU? d. What dipeptide is formed if a point mutation converts CAC to AAC and ACC to ACU?arrow_forwardDraw the complete structure of the ribonucleotide codon UAC. For what amino acid does this sequence code?arrow_forward
- In what direction is a new DNA strand formed?arrow_forwardGive an mRNA sequence that will code for the synthesis of angiotensin II. Asp-Arg-Val-Tyr-Ile-His-Pro-Phearrow_forwardThe following is a base sequence for an exon portion of a template strand of a DNA molecule: What is the base sequence of the hnRNA strand synthesized from the DNA template strand? What is the base sequence of the mRNA strand synthesized from the hnRNA strand? What codons are present in the mRNA strand produced from the DNA template strand? What tRNA molecule anticodons are needed to interact with the codons present in the mRNA strand produced from the template DNA strand?arrow_forward
- Predict the sequence of amino acids coded by the mRNA sequence 5AUGAAAGAAGACCUA3arrow_forwardThe -chain of hemoglobin is a protein that contains 146 amino acids residues. What minimum number of nucleotides must be present in a strand of mRNA that is coded for this protein?arrow_forward25-8 Draw the structures of ADP and GDP. Are these structures parts of nucleic acids?arrow_forward
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Nucleic acids - DNA and RNA structure; Author: MEDSimplified;https://www.youtube.com/watch?v=0lZRAShqft0;License: Standard YouTube License, CC-BY