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To explain: HoxA3 and HoxD3 genes are nearly equivalent yet they play distinct roles in the development of mouse.
Concept introduction: Hox genes belong to the Homeobox family of genes which play a crucial role in the development of organisms and several genes of the homeobox genes are conserved through evolution. HoxA3 is expressed in the pharynx, colon, ovary and many more. HoxD3 is expressed in the ovary, genital fat pad and many more. Cis- regulatory sequences or elements are non-coding regions present in the DNA and control the transcription of neighboring coding-regions present in DNA sequences.
To explain: The reason why the genes when transplaced could not perform their normal function in a new location.
Concept introduction: Hox genes belong to the Homeobox family of genes which play a crucial role in the development of organisms and several genes of the homeobox genes are conserved through evolution. HoxA3 is expressed in the pharynx, colon, ovary and many more. HoxD3 is expressed in the ovary, genital fat pad and many more. Cis- regulatory sequences or elements are non-coding regions present in the DNA and control the transcription of neighboring coding-regions present in DNA sequences.
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Chapter 21 Solutions
MOLECULAR BIOLOGY OF THE CELL
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- Choose a catecholamine neurotransmitter and describe/draw the components of the synapse important for its signaling including synthesis, packaging into vesicles, receptors, transporters/degradative enzymes. Describe 2 drugs that can act on this system.arrow_forwardThe following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. a) Which has a higher potency? b) Which is has a higher efficacy? c) What is the approximate Kd of capsaicin in uM? (you can round to the nearest power of 10)arrow_forwardWhat is the rate-limiting-step for serotonin synthesis?arrow_forward
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