CAMPBELL BIOLOGY,VOL.II >CUSTOM<
CAMPBELL BIOLOGY,VOL.II >CUSTOM<
17th Edition
ISBN: 9781323803677
Author: Urry
Publisher: PEARSON
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Chapter 20.3, Problem 3CC
Summary Introduction

To propose: An experiment to direct an embryonic stem cell or iPS cell to develop into a muscle cell.

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Embryonic stem cells or iPS (induced pluripotent) cells are undifferentiated cells and can develop into different cell types. They are stimulated to differentiate into specific cell types by different culture media, or modifying the cells by insertion of particular genes. Genetic engineering is the process of insertion of a target DNA segment consisting of a gene of interest from one organism to another. The inserted DNA segment expresses in the new genetically engineered organism.

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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences  A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?
Respond to the following in a minimum of 175 words: What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly? Provide an example of how you might explain these consequences in terms that patients might understand.
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