Microbiology: A Systems Approach
5th Edition
ISBN: 9781259706615
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Question
Chapter 20.3, Problem 12AYP
Summary Introduction
To explain:
The rationale behind the recommended treatment for HIV infection.
Concept introduction:
Virus is an infectious small particle that can’t be seen through the naked eyes. The human immunodeficiency virus is a lentivirus which is a causative agent of AIDS. This virus attacks T-cells, that provide immunity against the infection. The decline in number of T cells results in loss of the immunity and individual becomes susceptible to the virus. HIV enzyme, reverse transcriptase transcribes the viral genetic material RNA to DNA that can actively incorporate itself into the genetic material of the host causing AIDS.
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Students have asked these similar questions
19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 20 Solutions
Microbiology: A Systems Approach
Ch. 20.1 - Describe the important anatomical features of the...Ch. 20.1 - List the natural defenses present in the...Ch. 20.2 - Prob. 3AYPCh. 20.3 - Prob. 4AYPCh. 20.3 - Prob. 5AYPCh. 20.3 - Prob. 6AYPCh. 20.3 - Prob. 7AYPCh. 20.3 - Prob. 8AYPCh. 20.3 - Prob. 9AYPCh. 20.3 - Identify the five or six most relevant facts about...
Ch. 20.3 - Prob. 11AYPCh. 20.3 - Prob. 12AYPCh. 20.3 - Prob. 13AYPCh. 20 - Prob. 1MCQCh. 20 - Prob. 2MCQCh. 20 - Prob. 3MCQCh. 20 - Rabbit fever is caused by a. Yersinia pestis. b....Ch. 20 - Prob. 5MCQCh. 20 - Prob. 6MCQCh. 20 - Prob. 7MCQCh. 20 - Prob. 8MCQCh. 20 - Prob. 9MCQCh. 20 - Prob. 10MCQCh. 20 - Brucellosis can be transmitted to humans by...Ch. 20 - Prob. 12TFCh. 20 - Prob. 13TFCh. 20 - Prob. 14TFCh. 20 - Prob. 15TFCh. 20 - Explain why cases of dengue fever have been...Ch. 20 - Prob. 2CTQCh. 20 - Prob. 3CTQCh. 20 - Prob. 4CTQCh. 20 - Prob. 5CTQCh. 20 - Prob. 1VCCh. 20 - Prob. 1CM
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