Molecular Biology of the Cell (Sixth Edition)
6th Edition
ISBN: 9780815344322
Author: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher: W. W. Norton & Company
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Chapter 20, Problem 9P
Summary Introduction
To explain: The reason why the inhibitor should be designed for products of oncogenes or products of tumor suppressor genes
Concept introduction: Proto-oncogenes promote cell survival, cell growth and cell proliferation. Tumor suppressor genes regulate cell growth, cell survival and cell proliferation by inhibiting them. The mutations of proto-oncogenes are dominant or gain of function mutation and mutation of tumor suppressor genes are recessive or loss of function mutation.
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One of the ways for a cell to generate ATP is through the oxidative phosphorylation. In oxidative phosphorylation 3 ATP are produced from every one NADH molecule. In respiration, every glucose molecule produces 10 NADH molecules. If a cell is growing on 5 glucose molecules, how much ATP can be produced using oxidative phosphorylation/aerobic respiration?
If a cell is growing on 5 glucose molecules, how much ATP can be produced using oxidative phosphorylation/aerobic respiration?
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