EBK ORGANIC CHEMISTRY-PRINT COMPANION (
EBK ORGANIC CHEMISTRY-PRINT COMPANION (
4th Edition
ISBN: 9781119776741
Author: Klein
Publisher: WILEY CONS
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Chapter 20, Problem 87IP
Interpretation Introduction

Interpretation:

The enhanced reactivity of N-acetylazoles as compared to regular amides toward nucleophilic acyl substitution should be explained.

Concept introduction:

Aromatic compounds are highly stable due to the stabilization energy of their resonance.

Electrophile: An electrophile is a species that accepts a pair of electrons to form a new covalent bond.

To compare: The electrophilicity of carbonyl group in N-acetylazol and a regular amide.

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Chapter 20 Solutions

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