Microbiology: An Introduction
11th Edition
ISBN: 9780321733603
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: Benjamin Cummings
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Textbook Question
Chapter 20, Problem 5R
List the advantages of using two chemotherapeutic agents simultaneously to treat a disease. What problem can be encountered using two drugs?
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Check out a sample textbook solutionStudents have asked these similar questions
The type of antimicrobial drug that would be most likely to have toxic effects in
humans based on the premise of selective toxicity when treating microbial infection
would be a drug that
O 1) inhibits the synthesis of the cell wall
O 2) inhibits metabolic pathways
O 3) disrupts the cytoplasmic membrane
4) inhibits protein synthesis
5) All of the above have equal potential to be toxic
Name the five mechanisms of action we utilize to fight microorganisms and list one antibacterial drug for each.
When two antimicrobial drugs are used at the same time, antagonistic effects can occur. Which of the following is NOT a possible antagonistic effect of combining two antimicrobial drugs?
Increased elimination of one drug
Increased activity of both drugs
Increased toxicity
Decreased therapeutic levels
Decreased activity of both drugs
Chapter 20 Solutions
Microbiology: An Introduction
Ch. 20 - DRAW IT Show where the following antibiotics work:...Ch. 20 - List and explain five criteria used to identify an...Ch. 20 - What similar problems are encountered with...Ch. 20 - Define drug resistance. How is it produced? What...Ch. 20 - List the advantages of using two chemotherapeutic...Ch. 20 - Why does a cell die from the following...Ch. 20 - How does each of the following inhibit...Ch. 20 - The OH is missing from carbon 39 in ddI. How does...Ch. 20 - Compare the method of action of the following...Ch. 20 - NAME IT This microorganism is not susceptible to...
Ch. 20 - Which of the following pairs is mismatched? a....Ch. 20 - Prob. 2MCQCh. 20 - Prob. 3MCQCh. 20 - An antimicrobial agent should meet all of the...Ch. 20 - The most selective antimicrobial activity would be...Ch. 20 - Prob. 6MCQCh. 20 - Which of the following will not affect eukaryotic...Ch. 20 - Cell membrane damage causes death because a. the...Ch. 20 - A drug that intercalates into DNA has the...Ch. 20 - Chloramphenicol binds to the 50S portion of a...Ch. 20 - Prob. 1ACh. 20 - Why is idoxuridine effective if host cells also...Ch. 20 - Some bacteria become resistant to tetracycline...Ch. 20 - The following data were obtained from a...Ch. 20 - Prob. 5ACh. 20 - The following results were obtained from a broth...Ch. 20 - Vancomycin-resistant Enterococcus faecalis was...Ch. 20 - Prob. 2CAECh. 20 - Prob. 3CAE
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- What are the major causes of the ineffectiveness of anticancer therapies?arrow_forwardImportant characteristics of antimicrobial drugs include: a) readily delivered to the site of infection b) high toxicity against microbial cells c) do not cause serious side effects in humans d) remains active in body tissues and fluids e) all of the abovearrow_forwardWhich of the following would NOT be a reason that a clinical trial is unethical? a) Researchers are in a state of equipoise for the two treatments under study b) The sample size is very small c) The benefits to participants are outweighed by the potential risks d) The researchers already know that one treatment is better than the otherarrow_forward
- In a study on the effects of omega-3 fatty acids on patients with Alzheimer's disease, 80 women diagnosed with the disease were monitored. Over the 12 months of the study, 35 of the women received a daily omega-3 supplements and the rest received a placebo. This type of study is: A) a case study B) an epidemiological study C) a laboratory study D) an intervention studyarrow_forwardWhich of the following is true of selective toxicity? O 1) It refers to the process of determining the correct dose of a particular drug O 2) To be effective, an antimicrobial agent must be more toxic to the patient than 2) the pathogen O 3) It contributes to antibiotic resistance O 4) It refers to the body's ability to protect the brain and eye 5) It takes advantage of metabolic and structural differences between host and pathogenarrow_forwardWhere do chemotherapeutic agents come from?arrow_forward
- Below, you can see a picture of an antimicrobial drug. Regarding semi-synthetic antimicrobial drug development to try to avoid development of antibiotic resistance, use 1 sentence to address what is the significance/value of the presence of the various R-groups (e.g. R4, R5, R6, etc.)?arrow_forwardList some Characteristics of the Ideal Antimicrobial Drug.arrow_forwardWhich of the following inhibitors are correctly grouped? (Hint: same target) O cyanide, amytal, rotenon O oligomycin, antimycin A, piericidin O amytal, antimycin A, oligomycin O carbon monoxide, azide, cyanidearrow_forward
- The following are the limitations of Koch's postulates EXCEPT: A. some pathogens cannot grow on artificial media and therefore cannot be identified as the causative agent of the disease B. some diseases involve multiple pathogens which produce similar symptoms making it difficult to pinpoint the causative agent C. some diseases are host-specific and re-inoculation may pose ethical concerns D. some microorganisms are present in the body fluids of the infected animal which make them difficult to be culturedarrow_forwardNo one would dispute the facts that the use of antibiotics is extremely beneficial. Why then are there currently discussions around the idea that we as a society should be limiting our antibiotic use? What are the pros and cons of utilizing antibacterial and antimicrobial products (NOT antibiotics) on a daily basis? Do you agree or disagree that the use of antibiotics should be reduced and if so, how should it be done?arrow_forwardisolating a suspected agent in a sick individual that is absent in a healthy individual is sufficient to establish that the agent causes the disease? True or Falsearrow_forward
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