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Chapter 20, Problem 32RQ

Hyperglycemia in a diabetic patient leads to osmotic diuresis and dehydration. Given the following information, answer the questions.

Plasma glucose = 400 mg/dL

Normal urine flow = 1 L per day

GFR = 130 mL/min

Normal urine osmolarity = 300 mOsM

Glucose Tm = 400 mg/ min

Molecular mass of glucose = 180 daltons

Renal plasma flow = 500 mL/min

  1. a. How many milligrams of glucose filter into the nephron each minute?
  2. b. How many milligrams of glucose are reabsorbed each minute?
  3. c. How many grams of glucose are excreted in the urine each day?
  4. d. Assuming that dehydration causes maximal vasopressin secretion and allows the urine to concentrate to 1200 mOsM, how much additional urine does this diabetic patient excrete in a| day?
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Chapter 20 Solutions

Human Physiology: An Integrated Approach Plus Mastering A&P with Pearson eText -- Access Card Package (8th Edition) (What's New in Human Physiology)

Ch. 20.3 - A man comes to the doctor with high blood...Ch. 20.3 - Map the pathways through which elevated renin...Ch. 20.3 - Why is it more efficient to put ACE in the...Ch. 20.5 - Incorporate the thirst reflex into Figure 20.8.Ch. 20.6 - Map the pathway that begins with renal artery...Ch. 20.7 - CO2+H2OH++HCO3(6) In equation 6, the amount of...Ch. 20.7 - Why is ATP required for H+ secretion by the H+-K+...Ch. 20.7 - In hypokalemia, the intercalated cells of the...Ch. 20 - What is an electrolyte? Name five electrolytes...Ch. 20 - Prob. 2RQCh. 20 - Prob. 3RQCh. 20 - List the receptors that regulate osmolarity, blood...Ch. 20 - How do the two limbs of the loop of Henle differ...Ch. 20 - Prob. 6RQCh. 20 - Prob. 7RQCh. 20 - Prob. 8RQCh. 20 - Write out the words for the following...Ch. 20 - Prob. 10RQCh. 20 - Prob. 11RQCh. 20 - Prob. 12RQCh. 20 - Prob. 13RQCh. 20 - Prob. 14RQCh. 20 - Prob. 15RQCh. 20 - When ventilation increases, what happens to...Ch. 20 - Prob. 17RQCh. 20 - Figures 20.15 and 20.18a show the respiratory and...Ch. 20 - Explain how the loop of Henle and vasa recta work...Ch. 20 - Prob. 20RQCh. 20 - Prob. 21RQCh. 20 - Name the four main compensatory mechanisms for...Ch. 20 - Prob. 23RQCh. 20 - Compare and contrast the terms in each set: a....Ch. 20 - Prob. 25RQCh. 20 - Prob. 26RQCh. 20 - Prob. 27RQCh. 20 - Hannah, a 31-year-old woman, decided to have...Ch. 20 - Prob. 29RQCh. 20 - Prob. 30RQCh. 20 - The Henderson-Hasselbalch equation is a...Ch. 20 - Hyperglycemia in a diabetic patient leads to...Ch. 20 - Osmotic diuresis refers to the loss of additional...
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