Becker's World of the Cell (9th Edition)
Becker's World of the Cell (9th Edition)
9th Edition
ISBN: 9780321934925
Author: Jeff Hardin, Gregory Paul Bertoni
Publisher: PEARSON
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Chapter 20, Problem 20.11PS

(a)

Summary Introduction

To determine: Three possible explanations why the mutant form of mitotic cyclin is not degraded at the onset of anaphase.

Introduction: Usually mitotic cyclin, a protein, is selectively degraded at the onset of anaphase. Recombinant DNA techniques have been used to create a mutant form of the protein. It is seen that this protein is not degraded at the onset of anaphase.

(b)

Summary Introduction

To determine: Experiments that could be carried out to distinguish among the different explanations why the mutant form of mitotic cyclin is not degraded at the onset of anaphase.

Introduction: Usually mitotic cyclin, a protein, is selectively degraded at the onset of anaphase. Recombinant DNA techniques have been used to create a mutant form of the protein. It is seen that this protein is not degraded at the onset of anaphase.

(c)

Summary Introduction

To determine: The kind of protein in which mutation has occurred such that the results are altered.

Introduction: Usually mitotic cyclin, a protein, is selectively degraded at the onset of anaphase. Recombinant DNA techniques have been used to create a mutant form of the protein. It is seen that this protein is not degraded at the onset of anaphase. A mutation was seen in a second protein which also prevents degradation of mitotic cyclin.

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