What color would the bacterial cells appear in if the sample of the patient’s CSF were gram stained ; why the doctors suspected flu rather than melioidosis; why is it unlikely that there will be an epidemic of melioidosis in Norway or Sweden. Case summary: Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time. A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission. She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei . It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

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Answer 1

Question

Chapter 20, Problem 1EDCS

(1)

Summary Introduction

To determine:

What color would the bacterial cells appear in if the sample of the patient’s CSF were gram stained; why the doctors suspected flu rather than melioidosis; why is it unlikely that there will be an epidemic of melioidosis in Norway or Sweden.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

(2)

Summary Introduction

To define:

Why the doctors suspected flu rather than melioidosis.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

(3)

Summary Introduction

To define:

Why it is unexpected that there will be an outbreak of melioidosis in Norway or Sweden.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

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The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions. 1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction? 2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe: a) What molecule do you recommend for the trial. Why? b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for? 3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale. 4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale. Mutation 1 Mutation 2

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You have a bacterial strain with the CMU operon: a) As shown in the image below, the cmu operon encodes a peptide (Pep1), as well as a kinase and regulator corresponding to a two-component system. The cmu operon is activated when Pep 1 is added to the growth media. Pep1 is a peptide that when added extracellularly leads to activation of the Cmu operon. Pep1 cmu-kinase cmu-regulator You also have these genetic components in other strains: b) An alternative sigma factor, with a promoter activated by the cmu-regulator, that control a series of multiple operons that together encode a transformasome (cellular machinery for transformation). c) the gene cl (a repressor). d) the promoter X, which includes a cl binding site (and in the absence of cl is active). e) the gene gp (encoding a green fluorescence protein). Using the cmu operon as a starting point, and assuming you can perform cloning to rearrange any of these genomic features, how would you use one or more of these to modify the…

Answer 2

Question

Chapter 20, Problem 1EDCS

(1)

Summary Introduction

To determine:

What color would the bacterial cells appear in if the sample of the patient’s CSF were gram stained; why the doctors suspected flu rather than melioidosis; why is it unlikely that there will be an epidemic of melioidosis in Norway or Sweden.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

(2)

Summary Introduction

To define:

Why the doctors suspected flu rather than melioidosis.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

(3)

Summary Introduction

To define:

Why it is unexpected that there will be an outbreak of melioidosis in Norway or Sweden.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

Expert Solution & Answer

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Check out a sample textbook solution

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Answer 3

Question

Chapter 20, Problem 1EDCS

(1)

Summary Introduction

To determine:

What color would the bacterial cells appear in if the sample of the patient’s CSF were gram stained; why the doctors suspected flu rather than melioidosis; why is it unlikely that there will be an epidemic of melioidosis in Norway or Sweden.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

(2)

Summary Introduction

To define:

Why the doctors suspected flu rather than melioidosis.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

(3)

Summary Introduction

To define:

Why it is unexpected that there will be an outbreak of melioidosis in Norway or Sweden.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

Expert Solution & Answer

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Check out a sample textbook solution

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Answer 4

Question

Chapter 20, Problem 1EDCS

(1)

Summary Introduction

To determine:

What color would the bacterial cells appear in if the sample of the patient’s CSF were gram stained; why the doctors suspected flu rather than melioidosis; why is it unlikely that there will be an epidemic of melioidosis in Norway or Sweden.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

(2)

Summary Introduction

To define:

Why the doctors suspected flu rather than melioidosis.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

(3)

Summary Introduction

To define:

Why it is unexpected that there will be an outbreak of melioidosis in Norway or Sweden.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 20, Problem 1EDCS

(1)

Summary Introduction

To determine:

What color would the bacterial cells appear in if the sample of the patient’s CSF were gram stained; why the doctors suspected flu rather than melioidosis; why is it unlikely that there will be an epidemic of melioidosis in Norway or Sweden.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

(2)

Summary Introduction

To define:

Why the doctors suspected flu rather than melioidosis.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

(3)

Summary Introduction

To define:

Why it is unexpected that there will be an outbreak of melioidosis in Norway or Sweden.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

Answer 6

Chapter 20, Problem 1EDCS

(1)

Summary Introduction

To determine:

What color would the bacterial cells appear in if the sample of the patient’s CSF were gram stained; why the doctors suspected flu rather than melioidosis; why is it unlikely that there will be an epidemic of melioidosis in Norway or Sweden.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

Answer 7

Chapter 20, Problem 1EDCS

(1)

Summary Introduction

To determine:

What color would the bacterial cells appear in if the sample of the patient’s CSF were gram stained; why the doctors suspected flu rather than melioidosis; why is it unlikely that there will be an epidemic of melioidosis in Norway or Sweden.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

Answer 8

(2)

Summary Introduction

To define:

Why the doctors suspected flu rather than melioidosis.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

Answer 9

(2)

Summary Introduction

To define:

Why the doctors suspected flu rather than melioidosis.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

Answer 10

(3)

Summary Introduction

To define:

Why it is unexpected that there will be an outbreak of melioidosis in Norway or Sweden.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

Answer 11

(3)

Summary Introduction

To define:

Why it is unexpected that there will be an outbreak of melioidosis in Norway or Sweden.

Case summary:

Person I was a community college student who got the opportunity to help a professor to do research for a month in Northern Australia’s Kakadu National Park. She did not complain even though hiking the trails is hot and tiring. Things would be better if the thorns did not tear her legs regularly and if it did not seem to rain all the time.

A week later, after her return to Houston, she developed a high fever and general weakness. The blood work and all other signs appeared normal. Suspecting flu, the doctors told her to get plenty of rest and sent her back to home. Two days later, she was intermittently confused and felt drowsy, her breathing was labored, and a small cut on her leg was inflamed and was found to be a pus-filled lesion. She died the very next day following the hospital admission.

She died of an emerging disease called melioidosis, caused by a Gram-negative bacterium, Burkholderia pseudomallei. It produces a toxin that inhibits synthesis of proteins in the infected human cells. It is endemic to the Southeast Asia tropicals and appears to spread into more moderate climes. Person I had been infected either through inhalation or through an inflamed cut on her leg. Even with the treatment, 90% of melioidosis patients die.

Answer 12

Expert Solution & Answer

Answer 13

Expert Solution & Answer

Answer 14

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Answer 15

Ch. 20 - Prob. 1TMW Ch. 20 - Prob. 1EDCS Ch. 20 - Prob. 1CCS Ch. 20 - Prob. 2TMW Ch. 20 - Prob. 2CCS Ch. 20 - Prob. 2EDCS Ch. 20 - Prob. 3TMW Ch. 20 - Prob. 4TMW Ch. 20 - Prob. 3CCS Ch. 20 - Prob. 5TMW

Solution Summary: The author explains that Person I was infected with melioidosis, caused by a gram-negative bacterium, Burkholderia pseudomallei.

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Chapter 20 Solutions