Principles of Anatomy and Physiology
15th Edition
ISBN: 9781119329398
Author: Gerard J Tortora, Bryan Derrickson
Publisher: John Wiley & Sons Inc
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Chapter 20, Problem 16CP
Summary Introduction
To review:
Whether the amount of blood flowing through the coronary artery during ventricular diastole or ventricular systole is more or less.
Introduction:
Apart from the pulmonary and systemic circular, coronary circulation also takes place, which supplies blood to different regions of heart. The vessels that supply blood to the myocardium are a part of the coronary circulation. The oxygenated blood from the aorta in the left atrium is picked up by two coronary arteries, each entering into the left and right atrium.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 20 Solutions
Principles of Anatomy and Physiology
Ch. 20 - l. Define each of the following external features...Ch. 20 - 2. Describe the structure of the pericardium and...Ch. 20 - 3. What are the characteristic internal features...Ch. 20 - Prob. 4CPCh. 20 - 5. What is the relationship between wall thickness...Ch. 20 - Prob. 6CPCh. 20 - What causes the heart valves to open and to close?...Ch. 20 - In correct sequence, which heart chambers, heart...Ch. 20 - Prob. 9CPCh. 20 - Prob. 10CP
Ch. 20 - 11. In what ways are autorhythmic fibers similar...Ch. 20 - What happens during each of the three phases of an...Ch. 20 - 13. In what ways are ECGs helpful in diagnosing...Ch. 20 - How does each ECG wave, interval, and segment...Ch. 20 - 15. Why must left ventricular pressure be greater...Ch. 20 - Prob. 16CPCh. 20 - During which two periods of the cardiac cycle do...Ch. 20 - Prob. 18CPCh. 20 - Prob. 19CPCh. 20 - Prob. 20CPCh. 20 - Prob. 21CPCh. 20 - Define cardiac reserve. How does it change with...Ch. 20 - Prob. 23CPCh. 20 - 24. What are some of the cardiovascular benefits...Ch. 20 - Prob. 25CPCh. 20 - Prob. 26CPCh. 20 - Why is the cardiovascular system one of the first...Ch. 20 - From which tissue does the heart develop?Ch. 20 - Gerald recently visited the dentist. During the...Ch. 20 - 2. Unathletic Sylvia resolves to begin an exercise...Ch. 20 - 3. Mr. Perkins is a large, 62-year-old man with a...
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