Anatomy & Physiology
5th Edition
ISBN: 9780321861580
Author: Marieb, Elaine N.
Publisher: Pearson College Div
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Chapter 20, Problem 10CYU
Which of the following T cells would survive education in the thymus? (a) one that recognizes neither MHC nor self-antigen, (b) one that recognizes both MHC and self-antigen, (c) one that recognizes MHC but not self-antigen, (d) one that recognizes self-antigen but not MHC.
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Which of the following T cells would survive education in the thymus? (a) one that recognizes neither MHC nor self-antigen, (b) one that recognizes both MHC and self-antigen, (c) one that recognizes MHC but not self-antigen, (d) one that recognizes self-antigen but not MHC.
1. How does the thymus help the body avoid autoimmune responses?
(A) By negatively selecting T cells with receptors that bind to peptide-MHC complexes with high affinity.
(B) By positively selecting T cells with receptors that only recognize self peptides.
(C) By facilitating cell signaling between T cell surface receptors and antigens in the thymic capsule.
(D) By using clonal deletion to eliminate antigen-presenting cells that have low affinity for T cells receptors.
2. Functions of the innate immune system include all of these EXCEPT:
(A) to eliminate pathogens directly.
(B) to mediate the inflammatory response.
(C) to activate the adaptive immune system.
(D) All of these are functions of the innate immune system.
All of the following cells directly incorporate antigens into their structures, EXCEPT:
A). Antigen presenting cells.
B). Helper T cells
C). B cells
D). Killer T cells
Chapter 20 Solutions
Anatomy & Physiology
Ch. 20 - What distinguishes the innate defense system from...Ch. 20 - What is the first line of defense against disease?Ch. 20 - What is opsonization and how does it help...Ch. 20 - Under what circumstances might NK cells kill our...Ch. 20 - What are the cardinal signs of inflammation and...Ch. 20 - Name three key characteristics of adaptive...Ch. 20 - What is the difference between a complete antigen...Ch. 20 - What marks a cell as self as opposed to nonselfCh. 20 - What event (or observation) signals that a B or T...Ch. 20 - Which of the following T cells would survive...
Ch. 20 - Prob. 11CYUCh. 20 - In clonal selection, who does the selecting? What...Ch. 20 - Why is the secondary response to an antigen so...Ch. 20 - Prob. 14CYUCh. 20 - Which class of antibody is most abundant in blood?...Ch. 20 - List four ways in which antibodies can bring about...Ch. 20 - Class II MHC proteins display what kind of...Ch. 20 - Prob. 18CYUCh. 20 - Which type of T cell is the most important in both...Ch. 20 - Describe the killing mechanism of cytotoxic T...Ch. 20 - Prob. 21CYUCh. 20 - Prob. 22CYUCh. 20 - Prob. 23CYUCh. 20 - All of the following are considered innate body...Ch. 20 - The process by which neutrophils squeeze through...Ch. 20 - Antibodies released by plasma cells are involved...Ch. 20 - Which of the following antibodies can fix...Ch. 20 - Which antibody class is abundant in body...Ch. 20 - Small molecules that must combine with large...Ch. 20 - Lymphocytes that develop immunocompetence in the...Ch. 20 - Cells that can directly attack target cells...Ch. 20 - Prob. 9RQCh. 20 - The cell type most often invaded by HIV is a(n)...Ch. 20 - Complement fixation promotes all of the following...Ch. 20 - Using the letters from column B, match the cell...Ch. 20 - Besides acting as mechanical barriers, the skin...Ch. 20 - Explain why attempts at phagocytosis are not...Ch. 20 - What is complement? How does it cause bacterial...Ch. 20 - Interferons are referred to as antiviral proteins....Ch. 20 - Differentiate between humoral and cellular...Ch. 20 - Although the adaptive immune system has two arms,...Ch. 20 - Define immunocompetence and self-tolerance. How is...Ch. 20 - Differentiate between a primary and a secondary...Ch. 20 - Prob. 21RQCh. 20 - What is the role of the variable regions of an...Ch. 20 - Name the five antibody classes and describe where...Ch. 20 - How do antibodies help defend the body?Ch. 20 - Do vaccines produce active or passive humoral...Ch. 20 - Prob. 26RQCh. 20 - Describe the specific roles of helper, regulatory,...Ch. 20 - Prob. 28RQCh. 20 - Prob. 29RQCh. 20 - What events can result in autoimmune disease?Ch. 20 - Prob. 1CCSCh. 20 - Prob. 2CCSCh. 20 - Prob. 3CCSCh. 20 - Prob. 4CCSCh. 20 - Prob. 5CCS
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- What is the difference between innate immunity and adaptive immunity?arrow_forwardWhich statement best describes the difference between responses of effector B cells (plasma cells) and those of cytotoxic T cells? (A) B cells confer active immunity;cytotoxic T cells confer passive immunity. (B) B cells respond the first time a pathogen is present; cytotoxic T cells respond subsequent times. (C) B cells secrete antibodies against a pathogen; cytotoxic T cells kill pathogen-infected host cells. (D) B cells carry out the cell-mediated response; cytotoxic T cells carry out the humoral response.arrow_forwardPut the following steps in order for cell-mediated immunereactions:(a) Differentiated T cells include T helper, delayed hyper-sensitivity, cytotoxic, and memory T cells that all havedifferent immunological functions depending on the an-tigen presented.(b) Antigen-presenting cells (macrophages and dendriticcells) phagocytize pathogens, ingesting and degradingthem into pieces which are transported to the surface ofthe cell.(c) T cells bearing the corresponding receptor for the pre-sented antigen bind to it and become activated only ifthe appropriate MHC is also present.(d) Some pieces of the pathogen’s antigens are processedby inserting them into the antigen-presenting cell’smembrane and are held in place by class II majorhistocompatibility complex (MHCII) proteins.(e) Activated T cells are stimulated to divide and differen-tiate into different types of T cells, including memorycellsarrow_forward
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- Explain the mechanism by which (A) macrophages and NK cells, and (B) macrophages and effector T cells become mutually activated in the course of an innate and adaptive immune response, respectively. (C) Which gene defects would impair these mutual activation processes?arrow_forwardWhich of the following is NOT true of Innate Lymphoid Cells (ILCs)? A) Each ILC type responds to a different category of pathogens. b.)) ILCs are derived from the common lymphoid precursor. c. )) ILCs rearrange their antigen receptors in a similar way to T-cells. d. ))Each ILC type is distinguished by the cytokines that it produces. e. ))Development of each ILC type is driven by unique transcription factors.arrow_forwardCompare and contrast the morphology of the adult and infant thymus. (i) Describe 1 way that they are similar in structure and 1 way that they are different in structure? (ii) What do these differences signify about the role of the thymus in T cell development in infants versus adults?arrow_forward
- Perforins are destructive proteins associated with the activity of, (a) T cells. (b) B cells. (c) macrophages. (d) plasma cells.arrow_forwardB cell-receptors differ from T cell-receptors in that ________. A) B cell-receptors are immunoglobulins similar to those that are secreted, whereas T cell-receptors are not immunoglobulins and are never secreted B) T cell-receptors are much smaller than B cell-receptors C) All of the choices reflect differences between B cell- and T cell-receptors. D) B cell-receptors are comprised of four polypeptides, whereas T cell-receptors are made up of two polypeptidesarrow_forwardA person with AIDS will probably:(a) Not make antibody(b) Make a response to T-dependent antigens(c) Make antibody to T-independent antigens(d) Have large numbers of T-helper cells(e) None of the abovearrow_forward
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