To add: The monomers, polymers, dehydration synthesis , and hydrolysis to the concept map. Introduction: All organisms are made up of water and organic molecules that are essential to life. Generally, organisms contain various organic chemical compounds. Most of the organic molecules are occupied by carbon and hydrogen called hydrocarbons. Because it has a carbon atom that forms four covalent bonds with hydrogen atoms. This element combines with each other to form complex molecules, i.e., long chains, branched chains, and complex rings.

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Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 2, Problem 4PIT

Summary Introduction

To add:

The monomers, polymers, dehydration synthesis, and hydrolysis to the concept map.

Introduction:

All organisms are made up of water and organic molecules that are essential to life. Generally, organisms contain various organic chemical compounds. Most of the organic molecules are occupied by carbon and hydrogen called hydrocarbons. Because it has a carbon atom that forms four covalent bonds with hydrogen atoms. This element combines with each other to form complex molecules, i.e., long chains, branched chains, and complex rings.

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1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine: (a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data (c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip MAKE SURE ANSWERS HAVE UNITS if appropriate. SHOW ALL WORK, including equation used, variables used and each step to your solution.

2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0 Note that a µCi is a measure of the amount of radioactivity and hence is a measure of the amount of drug present. Given that the oral bioavailability of this drug is known to be essentially 100%, estimate the following from this…

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Answer 2

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Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 2, Problem 4PIT

Summary Introduction

To add:

The monomers, polymers, dehydration synthesis, and hydrolysis to the concept map.

Introduction:

All organisms are made up of water and organic molecules that are essential to life. Generally, organisms contain various organic chemical compounds. Most of the organic molecules are occupied by carbon and hydrogen called hydrocarbons. Because it has a carbon atom that forms four covalent bonds with hydrogen atoms. This element combines with each other to form complex molecules, i.e., long chains, branched chains, and complex rings.

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Answer 3

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Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 2, Problem 4PIT

Summary Introduction

To add:

The monomers, polymers, dehydration synthesis, and hydrolysis to the concept map.

Introduction:

All organisms are made up of water and organic molecules that are essential to life. Generally, organisms contain various organic chemical compounds. Most of the organic molecules are occupied by carbon and hydrogen called hydrocarbons. Because it has a carbon atom that forms four covalent bonds with hydrogen atoms. This element combines with each other to form complex molecules, i.e., long chains, branched chains, and complex rings.

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Check out a sample textbook solution

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Answer 4

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Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 2, Problem 4PIT

Summary Introduction