EP ESSENTIAL ORG.CHEM.-MOD.MASTERING
EP ESSENTIAL ORG.CHEM.-MOD.MASTERING
3rd Edition
ISBN: 9780133858501
Author: Bruice
Publisher: PEARSON CO
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Chapter 19.8, Problem 12P

Acid-catalyzed dehydration reactions are normally E1 reactions. Why is the acid-catalyzed dehydration in the second reaction of the citric acid cycle an E2 reaction?

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what is the mechnism of it?
Cholesterol-lowering drugs commonly target O HMG-COA synthase, the enzyme that catalyzes the synthesis of mevalonate O pyruvate decarboxylase complex, which catalyzes the synthesis of acetyl-CoA O mevalonate, an isoprene O HMG-COAreductase, the rate-limiting enzyme in cholesterol biosynthesis O HMG-CoA synthase, the enzyme that catalyzes the first step in cholesterol biosynthesis
Draw the products that form when the thioester CH3CH2CH2COSCoA is hydrolyzed with water. Differentiate products by greater or lesser molecular weight.
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