Campbell Biology: Custom Edition
18th Edition
ISBN: 9781323717271
Author: Urry, Cain, Wasserman, Minorsky, Reece
Publisher: PEARSON C
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Chapter 19.2, Problem 5CC
Summary Introduction
To propose a hypothesis: To identify ways to block the molecular pathway to fight HIV infection.
Concept introduction: HIV is a retrovirus having RNA as a genetic material. HIV mainly attacks the immune cells, especially CD4 cells. CD4 cells play an essential role by protecting the body from any infection. Antiretroviral therapy is a method of suppressing or preventing HIV infection using drugs, e.g., Tenofovir, Zidovudine.
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Introduction
You are a HIV researcher and the following questions depict your
struggles while developing, designing and interpreting
experiments. All the questions will relate to one another but you do
not need to do them in order. Each question will have multiple
parts and partial credit will be given whenever possible. Make sure
to use your book and notes to help understand the question and
develop your answers thoroughly.
Question 1
Your interest in HIV started with the protein below the protein below. 1HSG is a dimer and is
crystalized with a resolution of 1.9A. The active site is made up each dimer with one monomer in
blue and the other in red.
What two 2° structures are highlighted (with the black circle) in this figure?
The red amino acid sequence is; WKPKMIGGIGGFIKVRQY. What is the most likely sequence of the
circled portion? Explain how you choose this sequence
You did a BLAST analysis of your POI's and the following were returned as the first hits.
1DIF HIV-1 PROTEASE, 418Z…
Chapter 19 Solutions
Campbell Biology: Custom Edition
Ch. 19.1 - Prob. 1CCCh. 19.1 - MAKE CONNECTIONS Bacteriophages were used to...Ch. 19.2 - Compare the effect on the host cell of a lytic...Ch. 19.2 - MAKE CONNECTIONS Compare the CRISPR-Cas system to...Ch. 19.2 - Prob. 3CCCh. 19.2 - Why is HIV called a retrovirus?Ch. 19.2 - Prob. 5CCCh. 19.3 - Describe two ways in which a preexisting virus can...Ch. 19.3 - Contrast horizontal and vertical transmission of...Ch. 19.3 - WHAT IF? TMV has been isolated from virtually all...
Ch. 19 - Are viruses generally considered living or...Ch. 19 - Prob. 19.2CRCh. 19 - Prob. 19.3CRCh. 19 - Which of the following characteristics,...Ch. 19 - Emerging viruses arise by (A) mutation of existing...Ch. 19 - Prob. 3TYUCh. 19 - Prob. 4TYUCh. 19 - Prob. 5TYUCh. 19 - DRAW IT Redraw Figure 19.8 to show the replicative...Ch. 19 - EVOLUTION CONNECTION The successof some viruses...Ch. 19 - SCIENTIFIC INQUIRY When bacteria infect an animal,...Ch. 19 - WRITE ABOUT A THEME: ORGANIZATION While viruses...Ch. 19 - Prob. 10TYU
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