Genetics: A Conceptual Approach
Genetics: A Conceptual Approach
6th Edition
ISBN: 9781319050962
Author: Benjamin A. Pierce
Publisher: W. H. Freeman
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Chapter 19.2, Problem 2TPSQ
Summary Introduction

To determine:

The reason that researchers choose to cut out the entire exon 23 in the mice with the disorder.

Introduction:

CRISPR-Cas9 is a genome editing tool. It helps researchers to edit or change the gene from the genome of an organism. CRISPR stands for clustered regularly interspaced short palindromic repeats. They are found in the DNA sequence of the bacteria and archaea. By using the Cas9 enzyme, one can cut the targeted DNA and then make changes in the DNA. DNA repair system or machinery then fixes the DNA.

Summary Introduction

To determine:

The reason why researchers cannot replace specific mutation using a donor piece of DNA and homologous recombination

Introduction:

Mutation is when permanent alteration comes in the gene of the organism. It may be due to deletion, insertion, and duplication of the gene. Homologous recombination is the process in which nucleotides are exchanged between two similar or identical molecule of DNA.

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