EP HUMAN BIOLOGY-MODIFIED MASTERING
8th Edition
ISBN: 9780134326436
Author: Johnson
Publisher: PEARSON CO
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Chapter 19, Problem 9CR
Explain why lethal diseases caused by dominant alleles are so rare.
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Explain why disease alleles for cystic fibrosis (CF)are recessive to the normal alleles (CF+), yet thedisease alleles responsible for Huntington disease(HD) are dominant to the normal alleles (HD+).
Explain why most loss-of-function alleles are recessive to wild-type, but some are incompletely dominant or (rarely) dominant?
Huntington disease is a rare dominant disorder that causes neurodegeneration later in life. In a homozygous state, the dominant allele is lethal. A man in his thirties, who already has three children, discovers that his mother has Huntington disease though his father is unaffected. What are the following probabilities?
a) The man in his thirties will develop Huntington disease.
b) His first child will develop Huntington disease.
c) Any one out of three of his children will develop Huntington disease.
Chapter 19 Solutions
EP HUMAN BIOLOGY-MODIFIED MASTERING
Ch. 19 - If you might be a carrier of a gene for an...Ch. 19 - Prob. 2QCCh. 19 - Prob. 1CRCh. 19 - Prob. 2CRCh. 19 -
3. Distinguish between genotype and phenotype.
Ch. 19 - Describe the contributions of Mendel to the field...Ch. 19 - Explain how alterations of chromosome number and...Ch. 19 - Prob. 6CRCh. 19 - Prob. 7CRCh. 19 - Describe what is meant by sex-linked inheritance.
Ch. 19 -
9. Explain why lethal diseases caused by dominant...Ch. 19 - Prob. 10CRCh. 19 - All of the following statements about homologous...Ch. 19 - Prob. 2TYCh. 19 -
3. Which of the following statements correctly...Ch. 19 - Prob. 4TYCh. 19 - Prob. 5TYCh. 19 - Prob. 6TYCh. 19 - Prob. 7TYCh. 19 - Which of the following results in the separation...Ch. 19 - Prob. 9TYCh. 19 - Prob. 10TYCh. 19 - What tool is used to determine the probabilities...Ch. 19 - Prob. 12TYCh. 19 - What is the basis for the tremendous genetic...Ch. 19 - Prob. 14TYCh. 19 -
15. Which of the following events or processes...Ch. 19 -
1. What fraction of the offspring of two...Ch. 19 -
2. Why is it that the range of resting blood...Ch. 19 - Prob. 3AWKCh. 19 - Geneticists often study patterns of gene transfer...Ch. 19 - Prob. 5AWKCh. 19 - Prob. 6AWKCh. 19 - Nondisjunction during meiosis can lead to the...
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- Recognize progeny ratios that imply the existence ofrecessive lethal alleles.arrow_forwardExplain why most loss-of-function alleles (hypomorphic or amorphic) are recessive to wild-type alleles, but some are incompletely dominant or dominant.arrow_forwardA man with type A blood marries a woman with type B. Their offspring all have type AB blood. The pattern of inheritance is called A) codominance. B) sex-linkage. crossing over. incomplete dominancearrow_forward
- For an individual expressing the dominant phenotype, explain why you must list two possible genotypes.arrow_forwardfăctőrs suc 19) The genotype of a black snake is unknown. Black is a dominant allele, so the snake could be either BB or Bb. You cross this snake with a white snake (bb). Which of the following results of that cross would support the unknown genotype of the black snake being a homozygote? A) All F1 offspring are white B) All F1 offspring are black C) Half of the F1 offspring are white, the other half are black D) Three-quarters of the F1 offspring are black, the other quarter are white В x bb thearrow_forwardWhich statement is false when considering alleles and genes? a) A given gene can have many different possible alleles. b) Alleles are alternative forms or variants of genes. c) Individuals can be homozygous or heterozygous, and this refers to which alleles they have for a particular gene. d) An allele is the same thing as a gene.arrow_forward
- Dominant alleles are so called because under most circumstances they____ a) code for genes that are never considered lethal c) they are expressed whenever present d)code for desired traits only e) they are found on all 22 somatic chromosomes and not on sex chromosomesarrow_forwardOne form of the bleeding disorder known as von Willebrand disease is an autosomal recessive disease. A man who is a carrier marries a woman who is also a carrier of the disease. (a) What percentage of their children are likely to have a disease phenotype? (b) What percentage of their children are likely to have a normal phenotype? (c) What percentage of their children are likely to be carriers of the disease?arrow_forwardDuchennnes’s muscular dystrophy is caused by a rare sex-linked allele and usually affects only males. Victims of the disease become progressively weaker starting early in life. If your mother’s brother (your uncle) had Duchennes’s disease, what is the probability that you received the allele?arrow_forward
- In genetics, what does a genotype of Hh signify? Choose 1 answer: Choose 1 answer: (Choice A) A Homozygous; two dominant alleles (Choice B) B Homozygous; two recessive alleles (Choice C) C Heterozygous; one dominant allele and one recessive allele (Choice D) D Homozygous; one dominant allele and one recessive allelearrow_forwardExplain the following features of the Mendelian traits and fill the Punnet Squares. a)The disappearance of recessive phenotype in the F1 generation. b)The genotype of an individual expressing dominant phenotype can be differentiated by the test cross.arrow_forwardA case when a recessive allele would be expressed even when only one copy is present would be___ a ) recessive inheritance c ) multiple allele inheritance d ) sex - linked inheritance e ) incomplete dominancearrow_forward
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