Chapter 19, Problem 7CT

Summary Introduction

To explain: The probability that the children carry the sickle-cell trait and are sickle-cell anemic.

Introduction: Homozygous condition is when the same allele of a gene is present on both the homologous chromosomes either dominant or recessive. Heterozygous condition is where different alleles of the gene are present on both the homologous chromosomes where one is dominant and the other is recessive. Sickle-cell anemia occurs due to the homozygous recessive allele that changes the phenotype of the erythrocytes from biconcave to sickle-shaped.