Chapter 19, Problem 63TQ

Summary Introduction

To review:

The way in which errors made by aminoacyl-transfer ribonucleic acid (tRNA) synthetases are detected and corrected.

Introduction:

The aminoacyl tRNA synthetases are a versatile group of enzymes. These have a lot of variations in molecular weight, primary sequence, and thenumber of subunits. The specificity with which tRNAsynthetase produces correct aminoacyl-tRNA is the basis of translation. Sometimes, these enzymes produce errors due to the similarstructure of some amino acids.