To examine: Whether the statement “given the numerous processes inside cells that are regulated by changes in Ca +2 concentration, it seems likely that Ca +2 -dependent cell-cell adhesions are also regulated by changes in Ca +2 concentration” is true or false. Introduction: Cell-cell adhesions play an important role in maintaining the architecture of various tissues. The homophilic and heterophilic adhesion of cells is mediated by many cell-surface proteins (CAMs). CAMs are classified into five categories- cadherins, immunoglobulins, mucins, integrins, and selectins. Out of these, cadherin and selectin based cell adhesions depend on Ca +2 concentration.

Question

Want to see more full solutions like this?

Answer 1

Question

Chapter 19, Problem 1P

Summary Introduction

To examine: Whether the statement “given the numerous processes inside cells that are regulated by changes in Ca⁺² concentration, it seems likely that Ca⁺²-dependent cell-cell adhesions are also regulated by changes in Ca⁺² concentration” is true or false.

Introduction:

Cell-cell adhesions play an important role in maintaining the architecture of various tissues. The homophilic and heterophilic adhesion of cells is mediated by many cell-surface proteins (CAMs). CAMs are classified into five categories- cadherins, immunoglobulins, mucins, integrins, and selectins. Out of these, cadherin and selectin based cell adhesions depend on Ca⁺² concentration.

Expert Solution & Answer

Answer to Problem 1P

Correct answer: The statement is false.

Explanation of Solution

The regulation of various cell-cell interactions and processes are mediated by changes in Ca⁺² concentration through Ca⁺² signaling pathways. Cell surface proteins (CAMs) contribute in cell-cell adhesions. Cadherins come under Ca⁺²-dependent CAMs. The N-terminal extracellular domain is the site for binding of Ca⁺² and thus, adhesion of cells. The removal of Ca⁺² from extracellular medium dissociates the cells causing cadherins to mediate cell-cell adhesion. The cell-cell adhesion is not regulated by Ca⁺² concentration changes as cells cannot control Ca⁺² concentration in their environment. Hence, the statement is false.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Students have asked these similar questions

Question #3: In the KeyGene paper, the authors state that it would be useful if pollen from an apomict would transmit apomixis-inducing genes to the female in the cross (assuming the pollen is viable). Assuming there was just one gene conferring gametophytic obligate apomixis, and that the two parents are inbreds, what would be the consequences of such a cross if: a) The apomixis was a dominant trait? Indicate the genotypes and phenotypes (apomict or non- apomict) of the parents, F1 and F2 generations. Remember to include the expected genotypic and phenotypic ratios (or percentages) in the F1 and F2 generations, and to position the female first (left side) in the parental cross. b) The apomixis was a recessive trait? Indicate the genotypes and phenotypes (apomict or non- apomict) of the parents, F1 and F2 generations. Remember to include the expected genotypic and phenotypic ratios (or percentages) in the F1 and F2 generations, and to position the female first (left side) in the…

Question #5: Assume that two genes are identified that confer gametophytic facultative apomixis in soybean. The genes show independent assortment. Recessive alleles at both loci are required for the facultative apomixis. Facultative apomixis is triggered when the temperature at pollination is above 20 degrees C. At temperatures below 20 degrees C, all reproduction is sexual, independent of genotype. A facultative apomict male, capable of producing viable pollen, was crossed with a sexually reproducing female. Assuming the parents are completely inbred, what are the predicted phenotypic ratios (apomict: non-apomict) for the F1, F2, and DH (F1-derived) generations at each of the following temperatures*: a) 15°C? b) 25°C? *for full credit, show crosses and genotypes where appropriate. Remember to position the female first (left side) in the cross. Type your answer here:

a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved

Answer 2

Question

Chapter 19, Problem 1P

Summary Introduction

To examine: Whether the statement “given the numerous processes inside cells that are regulated by changes in Ca⁺² concentration, it seems likely that Ca⁺²-dependent cell-cell adhesions are also regulated by changes in Ca⁺² concentration” is true or false.

Introduction:

Cell-cell adhesions play an important role in maintaining the architecture of various tissues. The homophilic and heterophilic adhesion of cells is mediated by many cell-surface proteins (CAMs). CAMs are classified into five categories- cadherins, immunoglobulins, mucins, integrins, and selectins. Out of these, cadherin and selectin based cell adhesions depend on Ca⁺² concentration.

Expert Solution & Answer

Answer to Problem 1P

Correct answer: The statement is false.

Explanation of Solution

The regulation of various cell-cell interactions and processes are mediated by changes in Ca⁺² concentration through Ca⁺² signaling pathways. Cell surface proteins (CAMs) contribute in cell-cell adhesions. Cadherins come under Ca⁺²-dependent CAMs. The N-terminal extracellular domain is the site for binding of Ca⁺² and thus, adhesion of cells. The removal of Ca⁺² from extracellular medium dissociates the cells causing cadherins to mediate cell-cell adhesion. The cell-cell adhesion is not regulated by Ca⁺² concentration changes as cells cannot control Ca⁺² concentration in their environment. Hence, the statement is false.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 3

Question

Chapter 19, Problem 1P

Summary Introduction

To examine: Whether the statement “given the numerous processes inside cells that are regulated by changes in Ca⁺² concentration, it seems likely that Ca⁺²-dependent cell-cell adhesions are also regulated by changes in Ca⁺² concentration” is true or false.

Introduction:

Cell-cell adhesions play an important role in maintaining the architecture of various tissues. The homophilic and heterophilic adhesion of cells is mediated by many cell-surface proteins (CAMs). CAMs are classified into five categories- cadherins, immunoglobulins, mucins, integrins, and selectins. Out of these, cadherin and selectin based cell adhesions depend on Ca⁺² concentration.

Expert Solution & Answer

Answer to Problem 1P

Correct answer: The statement is false.

Explanation of Solution

The regulation of various cell-cell interactions and processes are mediated by changes in Ca⁺² concentration through Ca⁺² signaling pathways. Cell surface proteins (CAMs) contribute in cell-cell adhesions. Cadherins come under Ca⁺²-dependent CAMs. The N-terminal extracellular domain is the site for binding of Ca⁺² and thus, adhesion of cells. The removal of Ca⁺² from extracellular medium dissociates the cells causing cadherins to mediate cell-cell adhesion. The cell-cell adhesion is not regulated by Ca⁺² concentration changes as cells cannot control Ca⁺² concentration in their environment. Hence, the statement is false.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 4

Question

Chapter 19, Problem 1P

Summary Introduction

To examine: Whether the statement “given the numerous processes inside cells that are regulated by changes in Ca⁺² concentration, it seems likely that Ca⁺²-dependent cell-cell adhesions are also regulated by changes in Ca⁺² concentration” is true or false.

Introduction:

Cell-cell adhesions play an important role in maintaining the architecture of various tissues. The homophilic and heterophilic adhesion of cells is mediated by many cell-surface proteins (CAMs). CAMs are classified into five categories- cadherins, immunoglobulins, mucins, integrins, and selectins. Out of these, cadherin and selectin based cell adhesions depend on Ca⁺² concentration.

Expert Solution & Answer

Answer to Problem 1P

Correct answer: The statement is false.

Explanation of Solution

The regulation of various cell-cell interactions and processes are mediated by changes in Ca⁺² concentration through Ca⁺² signaling pathways. Cell surface proteins (CAMs) contribute in cell-cell adhesions. Cadherins come under Ca⁺²-dependent CAMs. The N-terminal extracellular domain is the site for binding of Ca⁺² and thus, adhesion of cells. The removal of Ca⁺² from extracellular medium dissociates the cells causing cadherins to mediate cell-cell adhesion. The cell-cell adhesion is not regulated by Ca⁺² concentration changes as cells cannot control Ca⁺² concentration in their environment. Hence, the statement is false.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 5

Chapter 19, Problem 1P

Summary Introduction

To examine: Whether the statement “given the numerous processes inside cells that are regulated by changes in Ca⁺² concentration, it seems likely that Ca⁺²-dependent cell-cell adhesions are also regulated by changes in Ca⁺² concentration” is true or false.

Introduction:

Cell-cell adhesions play an important role in maintaining the architecture of various tissues. The homophilic and heterophilic adhesion of cells is mediated by many cell-surface proteins (CAMs). CAMs are classified into five categories- cadherins, immunoglobulins, mucins, integrins, and selectins. Out of these, cadherin and selectin based cell adhesions depend on Ca⁺² concentration.

Expert Solution & Answer

Answer to Problem 1P

Correct answer: The statement is false.

Explanation of Solution

The regulation of various cell-cell interactions and processes are mediated by changes in Ca⁺² concentration through Ca⁺² signaling pathways. Cell surface proteins (CAMs) contribute in cell-cell adhesions. Cadherins come under Ca⁺²-dependent CAMs. The N-terminal extracellular domain is the site for binding of Ca⁺² and thus, adhesion of cells. The removal of Ca⁺² from extracellular medium dissociates the cells causing cadherins to mediate cell-cell adhesion. The cell-cell adhesion is not regulated by Ca⁺² concentration changes as cells cannot control Ca⁺² concentration in their environment. Hence, the statement is false.

Answer 6

Chapter 19, Problem 1P

Summary Introduction

To examine: Whether the statement “given the numerous processes inside cells that are regulated by changes in Ca⁺² concentration, it seems likely that Ca⁺²-dependent cell-cell adhesions are also regulated by changes in Ca⁺² concentration” is true or false.

Introduction:

Cell-cell adhesions play an important role in maintaining the architecture of various tissues. The homophilic and heterophilic adhesion of cells is mediated by many cell-surface proteins (CAMs). CAMs are classified into five categories- cadherins, immunoglobulins, mucins, integrins, and selectins. Out of these, cadherin and selectin based cell adhesions depend on Ca⁺² concentration.

Expert Solution & Answer

Answer to Problem 1P

Correct answer: The statement is false.

Explanation of Solution

The regulation of various cell-cell interactions and processes are mediated by changes in Ca⁺² concentration through Ca⁺² signaling pathways. Cell surface proteins (CAMs) contribute in cell-cell adhesions. Cadherins come under Ca⁺²-dependent CAMs. The N-terminal extracellular domain is the site for binding of Ca⁺² and thus, adhesion of cells. The removal of Ca⁺² from extracellular medium dissociates the cells causing cadherins to mediate cell-cell adhesion. The cell-cell adhesion is not regulated by Ca⁺² concentration changes as cells cannot control Ca⁺² concentration in their environment. Hence, the statement is false.

Answer 7

Chapter 19, Problem 1P

Summary Introduction

To examine: Whether the statement “given the numerous processes inside cells that are regulated by changes in Ca⁺² concentration, it seems likely that Ca⁺²-dependent cell-cell adhesions are also regulated by changes in Ca⁺² concentration” is true or false.

Introduction:

Cell-cell adhesions play an important role in maintaining the architecture of various tissues. The homophilic and heterophilic adhesion of cells is mediated by many cell-surface proteins (CAMs). CAMs are classified into five categories- cadherins, immunoglobulins, mucins, integrins, and selectins. Out of these, cadherin and selectin based cell adhesions depend on Ca⁺² concentration.

Answer 8

Expert Solution & Answer

Answer to Problem 1P

Correct answer: The statement is false.

Answer 9

Expert Solution & Answer

Answer 10

Expert Solution & Answer

Answer 11

Explanation of Solution

The regulation of various cell-cell interactions and processes are mediated by changes in Ca⁺² concentration through Ca⁺² signaling pathways. Cell surface proteins (CAMs) contribute in cell-cell adhesions. Cadherins come under Ca⁺²-dependent CAMs. The N-terminal extracellular domain is the site for binding of Ca⁺² and thus, adhesion of cells. The removal of Ca⁺² from extracellular medium dissociates the cells causing cadherins to mediate cell-cell adhesion. The cell-cell adhesion is not regulated by Ca⁺² concentration changes as cells cannot control Ca⁺² concentration in their environment. Hence, the statement is false.

Answer 12

Ch. 19 - Prob. 1P Ch. 19 - Prob. 2P Ch. 19 - Prob. 3P Ch. 19 - Prob. 4P Ch. 19 - Prob. 5P Ch. 19 - Prob. 6P Ch. 19 - Prob. 7P Ch. 19 - Prob. 8P Ch. 19 - Prob. 9P Ch. 19 - Prob. 10P

Concept explainers

Videos

Answer to Problem 1P

Explanation of Solution

Want to see more full solutions like this?

Chapter 19 Solutions