Antibiotic Effects on Mitochondria Tetracyclines are antibiotics that inactivate bacterial ribosomes. Knowing that mitochondria evolved from bacteria, researchers suspected tetracyclines might affect mitochondria by harming their ribosomes. FIGURE 19. 11 shows the effects of an experiment in which mice were given either tetracycline or a control antibiotic that affects cell wall production. After 10 days of treatment, the function of mitochondria in the mice was assessed. FIGURE 19.11 Effects of tetracycline on mitochondria . Mice received low-dose tetracycline, high-dose tetracycline, or a control antibiotic that targets bacterial cell walls. Mitochondrial function was assessed by looking at oxygen consumption rate and ATP content in homogenized mouse livers. Bar graphs show means with standard error. An * indicates a statistically significant difference between the experimental and the control treatments. How did the two drugs differ in their effect on oxygen consumption by mitochondria?

Question

Want to see more full solutions like this?

Answer 1

Textbook Question

Chapter 19, Problem 1DAA

Antibiotic Effects on Mitochondria Tetracyclines are antibiotics that inactivate bacterial ribosomes. Knowing that mitochondria evolved from bacteria, researchers suspected tetracyclines might affect mitochondria by harming their ribosomes. FIGURE 19. 11 shows the effects of an experiment in which mice were given either tetracycline or a control antibiotic that affects cell wall production. After 10 days of treatment, the function of mitochondria in the mice was assessed.

Chapter 19, Problem 1DAA, Antibiotic Effects on Mitochondria Tetracyclines are antibiotics that inactivate bacterial

FIGURE 19.11 Effects of tetracycline on mitochondria. Mice received low-dose tetracycline, high-dose tetracycline, or a control antibiotic that targets bacterial cell walls. Mitochondrial function was assessed by looking at oxygen consumption rate and ATP content in homogenized mouse livers. Bar graphs show means with standard error. An * indicates a statistically significant difference between the experimental and the control treatments.

How did the two drugs differ in their effect on oxygen consumption by mitochondria?

Expert Solution & Answer

Summary Introduction

To determine: The effects of control antibiotic and tetracycline on the oxygen consumption by mitochondria.

Concept introduction: Mitochondria are the powerhouse of the cell. It requires oxygen to produce the ATP in sufficient quantities to perform the energy-requiring reactions in eukaryotic organisms. Tetracycline is an antibiotic that works only against bacterial infections and does not work against viral infections.

Explanation of Solution

Control antibiotic, high dose and low dose of tetracycline are injected to the mice in order to check their oxygen consumption by the mitochondria. The graph shows that the control antibiotic results in higher oxygen consumption rate when compared to tetracycline. The mice that are injected with high and low dose of the tetracycline shows less oxygen consumption by the mitochondria than the control one.

Conclusion

Tetracycline antibiotics have an effect on the oxygen consumption rate in the mice.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Students have asked these similar questions

Please hand draw everying. Thank you! Draw a gram positive bacterial cell below. Your cell should have the following parts, labeled: A coccus shape A capsule The gram positive cell wall should have the peptidoglycan labeled, as well as its component parts (NAM, NAG, and teichoic acid) A cell membrane Fimbriae A nucleoid Ribosomes Inclusions

Draw a gram negative bacterial cell below. Your cell should have the following parts, labeled: A bacillus shape Fimbriae Amphitrichous flagella 2 membranes (outer and inner) The outer membrane should have lipopolysaccharide (LPS) with lipid A and O antigens Periplasmic space The thin peptidoglycan cell wall between the 2 membranes A nucleoid Ribosomes Inclusions

Bacterial species Cell wall type Example: S. mitis Gram positive S. epidermidis H. pylori M. bovis S. marcescens Shape and arrangement Coccus, streptococcus Drawing 0000000

Answer 2

Textbook Question

Chapter 19, Problem 1DAA

Antibiotic Effects on Mitochondria Tetracyclines are antibiotics that inactivate bacterial ribosomes. Knowing that mitochondria evolved from bacteria, researchers suspected tetracyclines might affect mitochondria by harming their ribosomes. FIGURE 19. 11 shows the effects of an experiment in which mice were given either tetracycline or a control antibiotic that affects cell wall production. After 10 days of treatment, the function of mitochondria in the mice was assessed.

Chapter 19, Problem 1DAA, Antibiotic Effects on Mitochondria Tetracyclines are antibiotics that inactivate bacterial

FIGURE 19.11 Effects of tetracycline on mitochondria. Mice received low-dose tetracycline, high-dose tetracycline, or a control antibiotic that targets bacterial cell walls. Mitochondrial function was assessed by looking at oxygen consumption rate and ATP content in homogenized mouse livers. Bar graphs show means with standard error. An * indicates a statistically significant difference between the experimental and the control treatments.

How did the two drugs differ in their effect on oxygen consumption by mitochondria?

Expert Solution & Answer

Summary Introduction

To determine: The effects of control antibiotic and tetracycline on the oxygen consumption by mitochondria.

Concept introduction: Mitochondria are the powerhouse of the cell. It requires oxygen to produce the ATP in sufficient quantities to perform the energy-requiring reactions in eukaryotic organisms. Tetracycline is an antibiotic that works only against bacterial infections and does not work against viral infections.

Explanation of Solution

Control antibiotic, high dose and low dose of tetracycline are injected to the mice in order to check their oxygen consumption by the mitochondria. The graph shows that the control antibiotic results in higher oxygen consumption rate when compared to tetracycline. The mice that are injected with high and low dose of the tetracycline shows less oxygen consumption by the mitochondria than the control one.

Conclusion

Tetracycline antibiotics have an effect on the oxygen consumption rate in the mice.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 3

Textbook Question

Chapter 19, Problem 1DAA

Antibiotic Effects on Mitochondria Tetracyclines are antibiotics that inactivate bacterial ribosomes. Knowing that mitochondria evolved from bacteria, researchers suspected tetracyclines might affect mitochondria by harming their ribosomes. FIGURE 19. 11 shows the effects of an experiment in which mice were given either tetracycline or a control antibiotic that affects cell wall production. After 10 days of treatment, the function of mitochondria in the mice was assessed.

Chapter 19, Problem 1DAA, Antibiotic Effects on Mitochondria Tetracyclines are antibiotics that inactivate bacterial

FIGURE 19.11 Effects of tetracycline on mitochondria. Mice received low-dose tetracycline, high-dose tetracycline, or a control antibiotic that targets bacterial cell walls. Mitochondrial function was assessed by looking at oxygen consumption rate and ATP content in homogenized mouse livers. Bar graphs show means with standard error. An * indicates a statistically significant difference between the experimental and the control treatments.

How did the two drugs differ in their effect on oxygen consumption by mitochondria?

Expert Solution & Answer

Summary Introduction

To determine: The effects of control antibiotic and tetracycline on the oxygen consumption by mitochondria.

Concept introduction: Mitochondria are the powerhouse of the cell. It requires oxygen to produce the ATP in sufficient quantities to perform the energy-requiring reactions in eukaryotic organisms. Tetracycline is an antibiotic that works only against bacterial infections and does not work against viral infections.

Explanation of Solution

Control antibiotic, high dose and low dose of tetracycline are injected to the mice in order to check their oxygen consumption by the mitochondria. The graph shows that the control antibiotic results in higher oxygen consumption rate when compared to tetracycline. The mice that are injected with high and low dose of the tetracycline shows less oxygen consumption by the mitochondria than the control one.

Conclusion

Tetracycline antibiotics have an effect on the oxygen consumption rate in the mice.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 4

Textbook Question

Chapter 19, Problem 1DAA

Antibiotic Effects on Mitochondria Tetracyclines are antibiotics that inactivate bacterial ribosomes. Knowing that mitochondria evolved from bacteria, researchers suspected tetracyclines might affect mitochondria by harming their ribosomes. FIGURE 19. 11 shows the effects of an experiment in which mice were given either tetracycline or a control antibiotic that affects cell wall production. After 10 days of treatment, the function of mitochondria in the mice was assessed.

Chapter 19, Problem 1DAA, Antibiotic Effects on Mitochondria Tetracyclines are antibiotics that inactivate bacterial

FIGURE 19.11 Effects of tetracycline on mitochondria. Mice received low-dose tetracycline, high-dose tetracycline, or a control antibiotic that targets bacterial cell walls. Mitochondrial function was assessed by looking at oxygen consumption rate and ATP content in homogenized mouse livers. Bar graphs show means with standard error. An * indicates a statistically significant difference between the experimental and the control treatments.

How did the two drugs differ in their effect on oxygen consumption by mitochondria?

Expert Solution & Answer

Summary Introduction

To determine: The effects of control antibiotic and tetracycline on the oxygen consumption by mitochondria.

Concept introduction: Mitochondria are the powerhouse of the cell. It requires oxygen to produce the ATP in sufficient quantities to perform the energy-requiring reactions in eukaryotic organisms. Tetracycline is an antibiotic that works only against bacterial infections and does not work against viral infections.

Explanation of Solution

Control antibiotic, high dose and low dose of tetracycline are injected to the mice in order to check their oxygen consumption by the mitochondria. The graph shows that the control antibiotic results in higher oxygen consumption rate when compared to tetracycline. The mice that are injected with high and low dose of the tetracycline shows less oxygen consumption by the mitochondria than the control one.

Conclusion

Tetracycline antibiotics have an effect on the oxygen consumption rate in the mice.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 5

Textbook Question

Answer 6

Textbook Question

Answer 7

Expert Solution & Answer

Summary Introduction

To determine: The effects of control antibiotic and tetracycline on the oxygen consumption by mitochondria.

Concept introduction: Mitochondria are the powerhouse of the cell. It requires oxygen to produce the ATP in sufficient quantities to perform the energy-requiring reactions in eukaryotic organisms. Tetracycline is an antibiotic that works only against bacterial infections and does not work against viral infections.

Explanation of Solution

Control antibiotic, high dose and low dose of tetracycline are injected to the mice in order to check their oxygen consumption by the mitochondria. The graph shows that the control antibiotic results in higher oxygen consumption rate when compared to tetracycline. The mice that are injected with high and low dose of the tetracycline shows less oxygen consumption by the mitochondria than the control one.

Conclusion

Tetracycline antibiotics have an effect on the oxygen consumption rate in the mice.

Answer 8

Expert Solution & Answer

Summary Introduction

To determine: The effects of control antibiotic and tetracycline on the oxygen consumption by mitochondria.

Concept introduction: Mitochondria are the powerhouse of the cell. It requires oxygen to produce the ATP in sufficient quantities to perform the energy-requiring reactions in eukaryotic organisms. Tetracycline is an antibiotic that works only against bacterial infections and does not work against viral infections.

Explanation of Solution

Control antibiotic, high dose and low dose of tetracycline are injected to the mice in order to check their oxygen consumption by the mitochondria. The graph shows that the control antibiotic results in higher oxygen consumption rate when compared to tetracycline. The mice that are injected with high and low dose of the tetracycline shows less oxygen consumption by the mitochondria than the control one.

Conclusion

Tetracycline antibiotics have an effect on the oxygen consumption rate in the mice.

Answer 9

Expert Solution & Answer

Answer 10

Expert Solution & Answer

Answer 11

Summary Introduction

To determine: The effects of control antibiotic and tetracycline on the oxygen consumption by mitochondria.

Concept introduction: Mitochondria are the powerhouse of the cell. It requires oxygen to produce the ATP in sufficient quantities to perform the energy-requiring reactions in eukaryotic organisms. Tetracycline is an antibiotic that works only against bacterial infections and does not work against viral infections.

Answer 12

Explanation of Solution

Control antibiotic, high dose and low dose of tetracycline are injected to the mice in order to check their oxygen consumption by the mitochondria. The graph shows that the control antibiotic results in higher oxygen consumption rate when compared to tetracycline. The mice that are injected with high and low dose of the tetracycline shows less oxygen consumption by the mitochondria than the control one.