To determine:
The reason for continuation of polio as an emergency for global public health.
Introduction:
Polio has no cure it can be stopped by immunization. The two vaccines are available for polio; (IPV) inactivated polio vaccine that has killed viruses and (OPV) oral polio vaccine that is attenuated.
The OPV is suggested by WHO for the eradication of polio from the globe. The children must get two drops per dose for getting immunized. The proper method of control suggests four doses of vaccine but the doses can be extended if surrounding conditions are very unhygienic and proclaiming reemergence of poliovirus.
Explanation of Solution
The polio expected to be eradicated from entire countries by the year 2012 but 3 countries came up with polio cases in year 2013. These countries were Pakistan, Afghanistan, and Nigeria. In addition, other countries also report certain cases of polio.
Earlier, these countries assumed to be polio free until new cases highlighted in the year 2013. The travelers advised to get booster vaccines before going out to the country or coming to country so that the virus cannot reach other countries. Children are not being immunized against polio because of various reasons. Some of them are geography, military and community issues, and unhygienic conditions.
The failure in complete vaccination “due to unhygienic conditions, difficulty in reaching remote area, and military and personal issues” against polio is causing re-emergence of polio; is a potential threat global public health.
To determine:
The difficulties in vaccinating children around the world and eradicating polio.
Introduction:
Polio has no cure, it can be stopped by immunization. The two vaccines are available for polio; (IPV) inactivated polio vaccine that has killed viruses and (OPV) oral polio vaccine that is attenuated.
The OPV is suggested by WHO for the eradication of polio from the globe. The children must get two drops per dose for getting immunized. The proper method of control suggests four doses of vaccine, but the doses can be extended if surrounding conditions are very unhygienic and proclaiming reemergence of poliovirus.
Explanation of Solution
The major issue related to reemergence of polio is complex geographical locations. It is difficult in providing vaccines in remote areas, such as mountainous countryside of countries such as Afghanistan and Pakistan. The needy children and affected people do not receive vaccines on time. Rarely, the vaccines are contributing to vaccine-associated paralytic polio.
The polio vaccines also not provided to countryside because of military and cultural reasons. The head of many communities denies vaccinating their children and increasing risk of getting their children infected and contributing to the reemergence of polio. The military heads do not allow the health care workers to cross-countryside such as Afghanistan and Pakistan in suspicion that they are agents.
The OPV contains live attenuated virus but some of viruses are able to revert and become virulent form that is causing a subset of vaccine related polio. In addition, polio has asymptomatic symptoms that help in silent transfer of virus in community and leads to outbreak.
These factors help to understand that the hundred percent of vaccination is necessary for global eradication of polio but due to difficulty in providing vaccines to all parts of the world, the polio is reemerging. In addition, due to military restrictions and cultural misnomers, the polio is re-emerging in certain countries.
Want to see more full solutions like this?
Chapter 19 Solutions
MICROBIOLOGY W/ACCESS
- A 10 mg/Kg dose of a drug is given by intravenous injection to a 20 Kg dog. What would the volume of distribution be if the drug had been given orally and only 50% of the drug was absorbed (the concentration of drug at time = 0 is 0.1 mg/L)? Be sure to show your work.arrow_forwardAfter oral administration of 10mg of a drug, 50% is absorbed and 40% of the amount absorbed is metabolized by the first pass effect. The bioavailable dose of this drug is ______. Make sure to provide units for your answer. Show your work.arrow_forwardA 10 mg/Kg dose of a drug is given by intravenous injection to a 20 Kg dog. What is the volume of distribution of the drug in liters if the plasma concentration is 0.1 mg/L (assume the drug is instantaneously distributed)? Be sure to show your work.arrow_forward
- Using a BLAST search, what class of proteins is similar to bovine angiogeninarrow_forwardIdentify an article within a Nursing Journal. Discuss how the issue within the article impact how we provide care. Please give in text citations and list references.arrow_forwardI have a question. I need to make 25 mL of this solution . How would I calculate the math? Please helparrow_forward
- Introduction to blood lab reportarrow_forwardWhich of the structural components listed in the Essential terms of section 1.3 (Cell components) could occur in a plant cell? Paragraph く BIUA 川く く 80 + кл Karrow_forwardWhich of the following statements refer(s) directly to the cell theory? (Note that one or more correct answers are possible.) Select 2 correct answer(s) a) There are major differences between plant and animal cells. b) There are major differences between prokaryote and eukaryote cells. c) All cells have a cell wall. d) All cells have a cell membrane. e) Animals are composed of cells. f) When a bacterial cell divides, it produces two daughter cells.arrow_forward
- Preoperative Diagnosis: Torn medial meniscus, left knee Postoperative Diagnosis: Combination horizontal cleavage tear/flap tear, posterior horn, medial meniscus, left knee. Operation: Arthroscopic subtotal medial meniscectomy, left knee Anesthetic: General endotracheal Description of Procedure: The patient was placed on the operating table in the supine position and general endotracheal anesthesia was administered. After an adequate level of anesthesia was achieved, the patient's left lower extremity was prepped with Betadine scrubbing solution, then draped in a sterile manner. Several sites were then infiltrated with 1% Xylocaine solution with Epinephrine to help control bleeding from stab wounds to be made at these sites. These stab wounds were made anterolaterally at the level of the superior pole of the patella for insertion of an irrigation catheter into the suprapatellar pouch area, anterolaterally at the level of the joint line for insertion of the scope and anteromedially at…arrow_forwardUARDIAN SIGNA Life Sciences/ Baseline Test Grade 10 ry must be written in point form. pot in full sentences using NO MORE than 70 words sentences from 1 to 7. only ONE point per sentence. words as far as possible. number of words you have used in brackets at the end GDE/2024 QUESTION 3 The table below shows the results of an investigation in which the effect of temperature and light on the yield of tomatoes in two greenhouses on a farm was investigated. TEMPERATURE (°C) AVERAGE YIELD OF TOMATOES PER 3.1 PLANT (kg) LOW LIGHT LEVELS HIGH LIGHT LEVELS 5 0,5 0,5 10 1,5 2,5 15 3,0 5,0 20 3,6 8,5 25 3,5 7,8 30 2,5 6,2 State TWO steps the investigator may have taken into consideration during the planning stage of the investigation. (2) 3.2 Identify the: a) Independent variables (2) b) Dependent variable (1) 3.3 Plot a line graph showing the results of the average yield of the tomatoes from 5°C to 30°C for low light levels. (6) 3.4 State ONE way in which the scientists could have improved the…arrow_forwardExplain why you chose this mutation. Begin by transcribing and translating BOTH the normal and abnormal DNA sequences. The genetic code below is for your reference. SECOND BASE OF CODON כ FIRST BASE OF CODON O THIRD BASE OF CODON SCAGUCAGUGAGUCAG UUU UUC UCU UAU UGU Phenylalanine (F) Tyrosine (Y) Cysteine (C) UCC UAC UGC Serine (S) UUA UUG Leucine (L) UCA UCG_ UAA UGA Stop codon -Stop codon UAG UGG -Tryptophan (W) CUU CUC CCU CAU CGU Histidine (H) CCC CAC CGC -Leucine (L) Proline (P) CUA CCA CAA CUG CCG CAG-Glutamine (Q) -Arginine (R) CGA CGG AUU ACU AAU AGU AUC Isoleucine (1) Asparagine (N) ACC AAC Threonine (T) AUA ACA AAA Methionine (M) Lysine (K) AUG ACG Start codon AAG AGC-Serine (S) -Arginine (R) AGA AGG GUU GCU GAU GUC GUA GUG GCC Valine (V) -Alanine (A) GCA GCG GAC GAA GAG Aspartic acid (D) GGU Glutamic acid (E) GGC GGA GGG Glycine (G) In order to provide a complete answer to the question stated above, fill in the mRNA bases and amino acid sequences by using the Genetic Code…arrow_forward
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education