EBK BIOLOGY
EBK BIOLOGY
10th Edition
ISBN: 8220100474729
Author: Martin
Publisher: Cengage Learning US
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Chapter 19, Problem 17TYU

INTERPRET DATA The recessive allele that causes Ellis–van Creveld syndrome when homozygous has a frequency of about 0.07 in the Amish population of Pennsylvania, although its frequency is only about 0.001 in the general population. How many persons out of one thousand in the Amish population would be expected to have the disease? How many out of one million in the general population?

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A form of learning disabilities and speech impairment results from a recessive mutation in the HERC2 gene. The next 4 questions are about this mutation. In a small Amish village in Ohio, about 5 per 1000 births are affected with this disorder.  Assume Hardy Weinberg equilibrium. What is the frequency of the dominant WT HERC2 allele in this small village? A form of learning disabilities and speech impairment results from a recessive mutation in the HERC2 gene. The next 4 questions are about this mutation. Part a: In a small Amish village in Ohio, about 5 per 1000 births are affected with this disorder.  Assume Hardy Weinberg equilibrium. What is the frequency of the dominant WT HERC2 allele in this small village? a)0.005 b)0.995 c)0.07 d)0.93   Part b: What is the estimated total number of homozygous dominant individuals in this village of 1000 people? a) 70 b) 930 c) 860 d) 140
You are an epidemiologist and come to an isolated village in the sub-Saharan African nation of Somalia. There are 300 people in this village and you diagnose 25 with sickle cell anemia, which is a recessive autosomal disorder. Assume the population is at Hardy- Weinberg equilibrium, and round to 3 decimals in your calculations. Part 1 What is the frequency of the recessive phenotyp What is the frequency of the recessive allele? Part 2 Given the frequency of the recessive allele, what is the frequency of the dominant allele? 0.711 0.917 0.957 0.830 0.250 0.289 0.083 0.083
.. Nowadays, newborn babies are required to be tested for phynylketonuria (PKU), an autosomal recessive genetic disorder. If untreated, individual homozygous for PKU suffer mental retardation. In a recent year, 4 PKU babies were detected out of 126,000 tested. Assuming Hardy-Weinberg conditions, what is the frequency of the PKU gene in this population (Give your answer in decimal number with 3 decimal places)?

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