
Concept explainers
(a)
Interpretation: The reagents that has to be used to prepare the given compound has to be identified.
Concept introduction: The nucleophile reacts with α, β- unsaturated
The alkylation at the β carbon of ketone or aldehyde is done by the following mechanism;
(1) Alkylating the β carbon via enamine intermediate.
(2) Alkylating the β carbon via a Michael reaction.
Michael reaction: The nucleophilic addition reaction of carboanion or some nucleophile to
(b)
Interpretation: The reagents that has to be used to prepare the given compound has to be identified.
Concept introduction: The nucleophile reacts with α, β- unsaturated aldehyde or ketones forming either direct addition product or conjugate addition product. When the nucleophile is a weak base conjugate addition product predominates.
The alkylation at the β carbon of ketone or aldehyde is done by the following mechanism;
(1) Alkylating the β carbon via enamine intermediate.
(2) Alkylating the β carbon via a Michael reaction.
Michael reaction: The nucleophilic addition reaction of carboanion or some nucleophile to

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Chapter 18 Solutions
Organic Chemistry; Modified MasteringChemistry with Pearson eText -- ValuePack Access Card; Study Guide and Student Solutions Manual for Organic Chemistry, Books a la Carte Edition (7th Edition)
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