Campbell Biology (10th Edition)
Campbell Biology (10th Edition)
10th Edition
ISBN: 9780321775658
Author: Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson
Publisher: PEARSON
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Chapter 18.4, Problem 2CC

MAKE CONNECTIONS Ø Explain how the signaling molecules released by an embryonic cell can induce changes in a neighboring cell without entering the cell. (See Figures 11.15 and 11.16.)

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MAKE CONNECTIONSPDGF signals cells by binding toa cell-surface receptor tyrosinekinase. If you added a chemicalthat blocked phosphorylation,how would the results differ?(See Figure 11.8.)
Discuss Signaling by Receptors that Interact with Cytoplasmic Janus Kinases?
a) Create a diagram which illustrates the typical signalling mechanism of action of kinase- linked receptors and possible routes of communication (autocrine etc.). Should show the specific molecules involved, the mechanisms of signal transduction and indicate the different pathways that are activated. It should include a specific example of a receptor, ligand and signalling pathway for each general class. Include as wide a variety of ligands and modes of action as you can. for a novel pathway. Superfamily Give the superfamily to which the receptor belongs Accession Give the Uniprot accession number Name Give the molecule name Species Give the species Ligand What is the ligand, or class of ligands which bind to this receptor? What are the physiological processes involved? Is this autocrine, paracrine or endocrine or some combination of them? What is the pathology of the receptor? Key physiological process involved Mechanism of What are the downstream actions of the receptor? Which…

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Campbell Biology (10th Edition)

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