Campbell Biology (10th Edition)
Campbell Biology (10th Edition)
10th Edition
ISBN: 9780321775658
Author: Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson
Publisher: PEARSON
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Chapter 18, Problem 13TYU
Summary Introduction

To describe: The experiment that proves the given hypothesis.

Hypothesis: “The female hormone estrogen activates genes controlled by androgen in prostate cancer cells”.

Introduction:

Androgen and estrogen are sex steroid hormones. They control the expression of male and female sexual characters, respectively. They function by binding and activating the intracellular receptors. These receptors act as ligand-dependent–specific transcription factors that stimulate the transcription of specific genes. Androgens are required for the survival of prostate cancer cells. There are certain prostate cancer cells that survive, despite the treatment that inhibits androgens. Both androgen and estrogen are steroid hormones and follow the same pathway for action. So, it can be hypothesized that estrogen activates genes in prostate cancer cells in the absence of androgen.

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19. On the diagram below a. Label the three pictures as: DNA; polypeptide; or RNA. b. Label the arrows as: translation or transcription/RNA processing. c. Add the following details to the diagram. Promoter region TATA box Transcription start site Transcription terminator Intron (A,B,C,D) Exons (1,2,3,4,5) Splice sites 5' cap 5' UTR (untranslated region) 3' poly A tail 3' UTR (untranslated region) Translational start (AUG) Translational stop (UGA, UAG, or UAA) N and C ends of polypeptide 0000
Match the letter labels in the figure below to the terms. Some letter labels are not used. MNNNNNNIN M C B A M D F E H K G 8

Chapter 18 Solutions

Campbell Biology (10th Edition)

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