Campbell Biology (10th Edition)
Campbell Biology (10th Edition)
10th Edition
ISBN: 9780321775658
Author: Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson
Publisher: PEARSON
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Chapter 18, Problem 13TYU
Summary Introduction

To describe: The experiment that proves the given hypothesis.

Hypothesis: “The female hormone estrogen activates genes controlled by androgen in prostate cancer cells”.

Introduction:

Androgen and estrogen are sex steroid hormones. They control the expression of male and female sexual characters, respectively. They function by binding and activating the intracellular receptors. These receptors act as ligand-dependent–specific transcription factors that stimulate the transcription of specific genes. Androgens are required for the survival of prostate cancer cells. There are certain prostate cancer cells that survive, despite the treatment that inhibits androgens. Both androgen and estrogen are steroid hormones and follow the same pathway for action. So, it can be hypothesized that estrogen activates genes in prostate cancer cells in the absence of androgen.

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calculate the questions showing the solution including variables,unit and equations all the questiosn below using the data.show solving and answer a) B1,   b) B2,   c) hybrid rate constant (1) d) hybrid rate constant (2) e) t1/2,dist t1/2,absorb f) t1/2,elim   k) apparent central compartment volume (V1,app) p) total AUC (using short cut method) apparent volume of distribution based on AUC (VAUC,app)  apparent clearance (CLapp)   absolute bioavailabilty of oral route ( AUCiv =116ml)
Please help me to draw this by hand. In as much detail as possible, hand draw a schematic diagram of the hypothalamic-pituitary-gonad (HPG) axis in the human female. Be sure to include all the relevant structures and hormones. You must define all abbreviations the first time you use them. Please include (and explain) the feedback loops.
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Chapter 18 Solutions

Campbell Biology (10th Edition)

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