MICRO. FUND. CONNECT CODE W/VIRTUAL LAB
MICRO. FUND. CONNECT CODE W/VIRTUAL LAB
3rd Edition
ISBN: 9781266313806
Author: Cowan
Publisher: INTER MCG
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Chapter 18.3, Problem 3NP
Summary Introduction

Introduction:

AIDS (autoimmune deficiency syndrome) is an asymptomatic infection which is defined by opportunistic series of HIV infection which causes immunosuppressed state. AIDS is caused by infection of HIV virus which uses integrase enzyme to integrate its nucleic acid into the genome of infected cell. HIV is transmitted through blood, semen, breast milk, sharing affected tattoo equipment, sexual intercourse, and affected milk.

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19. On the diagram below a. Label the three pictures as: DNA; polypeptide; or RNA. b. Label the arrows as: translation or transcription/RNA processing. c. Add the following details to the diagram. Promoter region TATA box Transcription start site Transcription terminator Intron (A,B,C,D) Exons (1,2,3,4,5) Splice sites 5' cap 5' UTR (untranslated region) 3' poly A tail 3' UTR (untranslated region) Translational start (AUG) Translational stop (UGA, UAG, or UAA) N and C ends of polypeptide 0000
Match the letter labels in the figure below to the terms. Some letter labels are not used. MNNNNNNIN M C B A M D F E H K G 8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions. 1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction? 2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe: a) What molecule do you recommend for the trial. Why? b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?  3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale. 4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale. Mutation 1 Mutation 2

Chapter 18 Solutions

MICRO. FUND. CONNECT CODE W/VIRTUAL LAB

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