Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 18, Problem 8QP
Summary Introduction
To determine: Whether the obtained results by the given pedigree analysis are satisfactory or not.
Introduction: The variations which occur in the genetic material of the organism from a source or randomly are called mutations. Single gene mutations can cause behavioral disorders in an organism.
Summary Introduction
To determine: The chances that tone deafness and perfect pitch can be alleles of a gene for musical ability.
Introduction: The variations which occur in the genetic material of the organisms from a source or randomly are called mutations. Single gene mutations can cause behavioral disorders in an organism.
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Concordance studies of twins for a neurodegenerative disorder show MZ=
46% and DZ= 15%. Further studies have shown a possible link to a gene
on chromosome 9, however, there are some individuals in the study who
have the allele but do not develop the disorder (group 1), and there are
other individuals who do not have the allele yet develop the disorder
(group 2). Amita's older sister and maternal uncle have this disorder.
Currently, Amita & her 2 younger brothers do not show symptoms. Amita's
paternal grandfather was rumored to have this disorder.
1. Draw the pedigree for Amita's family and determine the mode of
inheritance if any.
2. Explain how the 2 groups in the study could be possible?
3. What would you tell Amita about the heritability of this disorder?
In a cross in Drosophila, a female heterozygous for the autosomallylinked genes a, b, c, d, and e (abcde/ + + + + +) was testcrossedwith a male homozygous for all recessive alleles (abcde/abcde).Even though the distance between each of the loci was at least3 map units, only four phenotypes were recovered, yielding thefollowing data:
Phenotype No. of Flies+ + + + + 440a b c d e 460+ + + + e 48a b c d + 52 Total = 1000
Why are many expected crossover phenotypes missing? Can anyof these loci be mapped from the data given here? If so, determinemap distances.
Dominant negative
Incomplete dominance
Epistasis
Recessive lethal allele
III
|||
E
A condition where one gene has the ability to
override the expression of another gene no matter
what the relationship is between the other gene's
alleles.
A condition when a new mutation is able to suppress
or revert an earlier mutation allowing wildtype
function to reappear.
A condition where a recessive allele influences the
shape of a protein dimer product in the
heterozygous condition so that it neither resembles
the homozygous dominant nor the homozygous
recessive conditions leading to a LOF in the
heterozygous state and the recessive state.
A condition where two recessive alleles will be fatal
to an offspring although it will not affect a
Chapter 18 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 18.2 - What role would twin and adoption studies play in...Ch. 18.2 - Prob. 2EGCh. 18 - Why do you think it has been so difficult to...Ch. 18 - If a test were available that could tell you...Ch. 18 - Prob. 1QPCh. 18 - Prob. 2QPCh. 18 - Prob. 3QPCh. 18 - List the steps involved in transmitting a nerve...Ch. 18 - Why do neurotransmitters have to be removed from...Ch. 18 - Prob. 6QP
Ch. 18 - Perfect pitch is the ability to identify a note...Ch. 18 - Prob. 8QPCh. 18 - Name three genes whose mutations lead to an...Ch. 18 - Prob. 10QPCh. 18 - Prob. 11QPCh. 18 - Animal Models: The Search for Behavior Genes You...Ch. 18 - Prob. 13QPCh. 18 - A pedigree analysis was performed on the family of...Ch. 18 - Prob. 15QPCh. 18 - A region on chromosome 6 has been linked to...Ch. 18 - Genetics and Social Behavior Of the following...Ch. 18 - Prob. 18QPCh. 18 - Prob. 19QP
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