Anatomy & Physiology: The Unity of Form and Function
9th Edition
ISBN: 9781260791563
Author: Kenneth S. Saladin
Publisher: Mcgraw-hill Higher Education (us)
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Textbook Question
Chapter 17.4, Problem 11AYLO
How target cells modulate their hormone sensitivity
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 17 Solutions
Anatomy & Physiology: The Unity of Form and Function
Ch. 17.1 - Define the word hormone and distinguish a hormone...Ch. 17.1 - Prob. 2BYGOCh. 17.1 - Prob. 3BYGOCh. 17.1 - Prob. 4BYGOCh. 17.1 - Discuss why the target-cell concept is essential...Ch. 17.1 - The importance of intercellular communication for...Ch. 17.1 - The general term for the cells and glands that...Ch. 17.1 - Prob. 3AYLOCh. 17.1 - Prob. 4AYLOCh. 17.1 - Prob. 5AYLO
Ch. 17.2 - Prob. 6BYGOCh. 17.2 - Prob. 7BYGOCh. 17.2 - Prob. 8BYGOCh. 17.2 - In what sense does the pituitary take orders from...Ch. 17.2 - Prob. 10BYGOCh. 17.2 - Prob. 1AYLOCh. 17.2 - Prob. 2AYLOCh. 17.2 - Prob. 3AYLOCh. 17.2 - Two hormones synthesized in the hypothalamus and...Ch. 17.2 - Prob. 5AYLOCh. 17.2 - Two hormones secreted by the posterior pituitary,...Ch. 17.2 - Prob. 7AYLOCh. 17.2 - Prob. 8AYLOCh. 17.3 - Prob. 11BYGOCh. 17.3 - Prob. 12BYGOCh. 17.3 - Prob. 13BYGOCh. 17.3 - Prob. 14BYGOCh. 17.3 - Prob. 15BYGOCh. 17.3 - Prob. 16BYGOCh. 17.3 - Prob. 1AYLOCh. 17.3 - Prob. 2AYLOCh. 17.3 - Prob. 3AYLOCh. 17.3 - Anatomy of the parathyroid glands; their hormone...Ch. 17.3 - Prob. 5AYLOCh. 17.3 - Prob. 6AYLOCh. 17.3 - Three tissue zones of the adrenal cortex, the...Ch. 17.3 - Prob. 8AYLOCh. 17.3 - Prob. 9AYLOCh. 17.3 - Hormones produced by the following tissues and...Ch. 17.4 - What are the three chemical classes of hormones?...Ch. 17.4 - Prob. 18BYGOCh. 17.4 - Prob. 19BYGOCh. 17.4 - Prob. 20BYGOCh. 17.4 - Prob. 21BYGOCh. 17.4 - Prob. 1AYLOCh. 17.4 - Prob. 2AYLOCh. 17.4 - Prob. 3AYLOCh. 17.4 - Prob. 4AYLOCh. 17.4 - The Types of stimuli that elicit hormone...Ch. 17.4 - Thyroid hormone synthesis and secretionCh. 17.4 - Prob. 7AYLOCh. 17.4 - Prob. 8AYLOCh. 17.4 - Which hormones require second messengers to...Ch. 17.4 - How signal amplification enables small amounts of...Ch. 17.4 - How target cells modulate their hormone...Ch. 17.4 - Three kinds of interactions that can occur when...Ch. 17.4 - Prob. 13AYLOCh. 17.5 - Define stress from the standpoint of...Ch. 17.5 - Describe the stages of the general adaptation...Ch. 17.5 - Prob. 24BYGOCh. 17.5 - Prob. 1AYLOCh. 17.5 - Prob. 2AYLOCh. 17.5 - The three stages of the stress response; the...Ch. 17.6 - Prob. 25BYGOCh. 17.6 - Prob. 26BYGOCh. 17.6 - Prob. 27BYGOCh. 17.6 - Paracrine and autocrine secretions, examples, and...Ch. 17.6 - The general structure and metabolic precursor of...Ch. 17.6 - Prob. 3AYLOCh. 17.6 - Prob. 4AYLOCh. 17.6 - Prob. 5AYLOCh. 17.7 - Prob. 28BYGOCh. 17.7 - Prob. 29BYGOCh. 17.7 - Prob. 30BYGOCh. 17.7 - Prob. 1AYLOCh. 17.7 - Myxedema, endemic goiter, and toxic goiterCh. 17.7 - Effects of hypo- and hyperparathyroidismCh. 17.7 - Cushing syndrome and adrenogenital syndromeCh. 17.7 - Prob. 5AYLOCh. 17.7 - Prob. 6AYLOCh. 17.7 - Prob. 7AYLOCh. 17.7 - Consequences of inadequately treated DM and why...Ch. 17 - CRH secretion would not raise the blood...Ch. 17 - Prob. 2TYRCh. 17 - Prob. 3TYRCh. 17 - Prob. 4TYRCh. 17 - Prob. 5TYRCh. 17 - Prob. 6TYRCh. 17 - Prob. 7TYRCh. 17 - Prob. 8TYRCh. 17 - Prob. 9TYRCh. 17 - Prostaglandins are derived from a. phospholipase....Ch. 17 - Prob. 11TYRCh. 17 - Prob. 12TYRCh. 17 - Growth hormone hypersecretion in adulthood causes...Ch. 17 - Prob. 14TYRCh. 17 - Prob. 15TYRCh. 17 - Prob. 16TYRCh. 17 - Target cells can reduce pituitary secretion by a...Ch. 17 - Prob. 18TYRCh. 17 - Prob. 19TYRCh. 17 - ______ is a process in which a cell increases its...Ch. 17 - adeno-Ch. 17 - Prob. 2BYMVCh. 17 - Prob. 3BYMVCh. 17 - Prob. 4BYMVCh. 17 - Prob. 5BYMVCh. 17 - Prob. 6BYMVCh. 17 - Prob. 7BYMVCh. 17 - Prob. 8BYMVCh. 17 - Prob. 9BYMVCh. 17 - Prob. 10BYMVCh. 17 - Castration would lower a mans blood gonadotropin...Ch. 17 - Prob. 2WWTSCh. 17 - Prob. 3WWTSCh. 17 - Prob. 4WWTSCh. 17 - Prob. 5WWTSCh. 17 - The great majority of cases of diabetes mellitus...Ch. 17 - Prob. 7WWTSCh. 17 - A deficiency of dietary iodine would lead to...Ch. 17 - Prob. 9WWTSCh. 17 - Prob. 10WWTSCh. 17 - Prob. 1TYCCh. 17 - Suppose you were browsing in a health-food store...Ch. 17 - Prob. 3TYCCh. 17 - Prob. 4TYCCh. 17 - A young man is involved in a motorcycle accident...
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