ANAT & PHYS: INTEGRATIVE APPROACH
3rd Edition
ISBN: 9781260577853
Author: McKinley
Publisher: MCG
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
Chapter 17.11, Problem 35WDL
Summary Introduction
To determine:
The organ that releases angiotensinogen, and the function of angiotensinogen following its activation.
Introduction:
The liver releases angiotensinogen hormone among insulin-like growth factors. Angiotensinogen is released in an inactive form. Angiotensinogen is converted into active form angiotensin II by two enzymes. One of them releases from the kidney that is rennin and another enzyme releases from the inner lining of the blood vessels that is angiotensin-converting enzyme or ACE.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
According to a recent study, 1 out of 50,000 people will be diagnosed with
cystic fibrosis. Cystic fibrosis can be caused by a mutant form of the CFTR gene
(dominant gene symbol is F and mutant is f).
A. Using the rate of incidence above, what is the frequency of carriers of the
cystic fibrosis allele for CFTR in the US? (3 pts)
B. In a clinical study, 400 people from the population mentioned in (A.) were
genotyped for BRCA1 Listed below are the results. Are these results in Hardy-
Weinberg equilibrium? Use Chi Square to show whether or not they are. (3 pts)
BRCA1 genotype
# of women
390
BB
Bb
bb
10
0
12pt
Paragraph
L
BIUAV V
T² v
V
Outline a method for using apomixis to maintain feminized CannabisAssume apomixis is controlled by a single dominant gene. You can choose the type of apomixis: obligate or facultative, gametophytic or sporophytic. Discuss advantages and disadvantages of your proposed method.
Kinetics: One-Compartment First-Order Absorption
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration.
Using this data and set of graphs, determine:(calculate for each variable)
(a) k, C0, V, and AUC* for the bolus iv data
(b) k, ka, B1, and AUC* for the po data
c) k, ka, B1, and AUC* for the ip data
(d) relative bioavailability for po vs ip, Fpo/Fip
(e)absolute ip bioavailability, Fip
(f) absolute po bioavailability, Fpo
Chapter 17 Solutions
ANAT & PHYS: INTEGRATIVE APPROACH
Ch. 17.1 - Prob. 1LOCh. 17.1 - Prob. 1WDLCh. 17.1 - Prob. 2LOCh. 17.1 - How does the endocrine system differ from the...Ch. 17.1 - Prob. 3LOCh. 17.1 - Diabetes mellitus is noted by sustained high blood...Ch. 17.2 - Prob. 4LOCh. 17.2 - Prob. 4WDLCh. 17.2 - Prob. 5LOCh. 17.2 - Adrenocorticotropic hormone (ACTH) stimulates the...
Ch. 17.3 - Prob. 6LOCh. 17.3 - Prob. 7LOCh. 17.3 - Identify which of the following hormone categories...Ch. 17.3 - What two events or processes associated with a...Ch. 17.3 - Prob. 8LOCh. 17.3 - Prob. 9LOCh. 17.3 - Prob. 1WDTCh. 17.3 - Prob. 8WDLCh. 17.4 - Prob. 10LOCh. 17.4 - Why are carrier proteins necessary for...Ch. 17.4 - What is the added benefit of a carrier protein?Ch. 17.4 - Prob. 11LOCh. 17.4 - Prob. 12LOCh. 17.4 - Prob. 2WDTCh. 17.4 - What is the relationship of hormone synthesis to...Ch. 17.5 - Prob. 13LOCh. 17.5 - Where are lipid-soluble hormone receptors located?...Ch. 17.5 - Prob. 14LOCh. 17.5 - Prob. 13WDLCh. 17.6 - Prob. 15LOCh. 17.6 - Prob. 16LOCh. 17.6 - Prob. 3WDTCh. 17.6 - How does down-regulation of cellular receptors...Ch. 17.6 - Prob. 17LOCh. 17.6 - What effects are seen when hormones act...Ch. 17.7 - Prob. 18LOCh. 17.7 - Prob. 19LOCh. 17.7 - What is the anatomic connection between the...Ch. 17.7 - Prob. 20LOCh. 17.7 - Prob. 4WDTCh. 17.7 - Prob. 17WDLCh. 17.7 - Prob. 21LOCh. 17.7 - Prob. 22LOCh. 17.7 - Prob. 18WDLCh. 17.7 - Prob. 23LOCh. 17.7 - Prob. 24LOCh. 17.7 - Prob. 5WDTCh. 17.7 - Prob. 19WDLCh. 17.7 - Prob. 20WDLCh. 17.8 - Prob. 25LOCh. 17.8 - Prob. 26LOCh. 17.8 - Prob. 6WDTCh. 17.8 - Prob. 21WDLCh. 17.8 - Prob. 27LOCh. 17.8 - Prob. 7WDTCh. 17.8 - What is the relationship of TRH, TSH, and TH in...Ch. 17.8 - What are the primary target organs/issues of TH?...Ch. 17.8 - Prob. 28LOCh. 17.9 - Prob. 24WDLCh. 17.9 - Prob. 29LOCh. 17.9 - Prob. 30LOCh. 17.9 - Prob. 25WDLCh. 17.9 - LEARNING OBJECTIVE
31. Describe the homeostatic...Ch. 17.9 - Prob. 26WDLCh. 17.9 - What are the primary target organs/tissues of...Ch. 17.10 - Prob. 32LOCh. 17.10 - Prob. 33LOCh. 17.10 - Why is the pancreas considered both an exocrine...Ch. 17.10 - Prob. 34LOCh. 17.10 - Prob. 35LOCh. 17.10 - Prob. 8WDTCh. 17.10 - Is the stimulus for insulin and glucagon release...Ch. 17.10 - What is the stimulus, receptor, control center,...Ch. 17.10 - Which of these hormones causes release of glucose...Ch. 17.11 - LEARNING OBJECTIVE
36. Describe the general...Ch. 17.11 - How do melatonin levels change throughout the day?Ch. 17.11 - LEARNING OBJECTIVE
37. Describe the general...Ch. 17.11 - What is the primary hormone released from the...Ch. 17.11 - Prob. 38LOCh. 17.11 - Prob. 34WDLCh. 17.11 - Prob. 35WDLCh. 17.12 - Prob. 39LOCh. 17.12 - What general changes occur to the ability of...Ch. 17 - Prob. 1DYBCh. 17 - This hormones primary function is to regulate...Ch. 17 - Which of the following are components of...Ch. 17 - A hormone released from the anterior pituitary is...Ch. 17 - Prob. 5DYBCh. 17 - Prob. 6DYBCh. 17 - Glucagon has an __________ effect to insulin on...Ch. 17 - Glucocorticoids (e.g., cortisol) are produced in...Ch. 17 - Prob. 9DYBCh. 17 - All of the following hormones are released from...Ch. 17 - Prob. 11DYBCh. 17 - Prob. 12DYBCh. 17 - Explain the three mechanisms used to stimulate...Ch. 17 - Identify the three chemical classes of hormones,...Ch. 17 - Describe how local hormones differ from...Ch. 17 - Explain the function of carrier proteins in...Ch. 17 - Describe how water-soluble hormones interact with...Ch. 17 - Explain how the hypothalamus oversees and controls...Ch. 17 - Explain how the hypothalamus oversees and controls...Ch. 17 - Discuss the homeostatic system involving insulin.Ch. 17 - George is a 43-year-old construction worker who...Ch. 17 - What is the best diagnostic test to determine if...Ch. 17 - Jelena is late for work and is rushing to get out...Ch. 17 - Blood samples from a young woman named Michelle...Ch. 17 - Stephen is taking a new weight-loss supplement...Ch. 17 - Prob. 1CSLCh. 17 - Prob. 2CSLCh. 17 - Henry is a well-informed patient who is interested...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- 3. A promising new drug is being evaluated in human trials. Based on preliminary human tests, this drug is most effective when plasma levels exceed 30 mg/L. Measurements from preliminary tests indicate the following human pharmacokinetic parameter values: t1/2,elim = 4.6hr, t1/2,abs = 0.34hr, VD = 0.29 L/kg, Foral = 72%. Based on these parameters, estimate the following if a 49 kg woman were to receive a 1000mg oral dose of this drug: (a) Estimate the plasma concentration of the drug at 1hr, 6 hr, and 20hr after taking the drug ( Concentration estimate) (b) Estimate the time for maximum plasma concentration (tmax). (c) Estimate the maximum plasma concentration (Cmax). (d) Estimate the time at which the plasma level first rises above 30 mg/L. (Note this is a trial and error problem where you must guess a time, plug it into the concentration equation, and determine if it is close to 30 mg/L. Hint: based on part (a) it should be apparent that the answer is less than 1hr.) (e)…arrow_forwardList substitutions in your diet you could make to improve it based on what you know now about a balanced diet. For instance, if you like to drink soda, you might substitute skim milk or water for some of the soft drinks you consumed. List the item you wish to replace with the new item and what you hope to accomplish with that substitution. Be sure to choose foods you know that you'd enjoy and you consider more "healthful." If you feel your diet is already balanced, describe how you accomplish your balanced intake and when you began eating this way.arrow_forwardWhich single food item contained you ate for the 3 days with the most sodium?arrow_forward
- Select a diet and choose one site that provides credible information. Explain why the source itself and/or the information on the site is credible. This should be a report. This site should be different from U.S News and World Report. For full credit, you must include the following information and elaborate in detail: The diet name The main components of the diet The credible website name and link What makes the credible website credible?arrow_forwardSelect a diet and give a summary of the main components. Do a web search of the diet and choose one link that provides misinformation. Explain why the site itself and/or the information on the site is not credible. This should be a report. This site should be different from U.S News and World Report. For full credit, you must include the following information and elaborate in detail: The diet name The main components of the diet The misinformation website and link What misinformation is being provided in the other website and how did you determine it was not credible?arrow_forward1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine: (a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data (c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip MAKE SURE ANSWERS HAVE UNITS if appropriate. SHOW ALL WORK, including equation used, variables used and each step to your solution.arrow_forward
- 2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0 Note that a µCi is a measure of the amount of radioactivity and hence is a measure of the amount of drug present. Given that the oral bioavailability of this drug is known to be essentially 100%, estimate the following from this…arrow_forwardThe current nutrition labelling regulation in Hong Kong requires food manufacturer to list E+7 information on the package of pre-packaged food products. Do you think that more nutrients, such as calcium and cholesterol, shall be included?arrow_forwardView History Bookmarks Window Help Quarter cements ents ons (17) YouTube Which amino acids would you expect to find marked on the alpha helix? canvas.ucsc.edu ucsc Complaint and Grievance Process - Academic Personnel pach orations | | | | | | | | | | | | | | | | 000000 000000000 | | | | | | | | | | | | | | | | | | | | | | 00000000 scope vious De 48 12.415 KATPM FEB 3 F1 F2 80 F3 a F4 F5 2 # 3 $ 85 % tv N A の Mon Feb 3 10:24 PM Lipid bilayer Submit Assignment Next > ZOOM < Å DII 8 བ བ F6 16 F7 F8 F9 F10 34 F11 F12 & * ( 6 7 8 9 0 + 11 WERTY U { 0 } P deletearrow_forward
- Different species or organisms research for ecologyarrow_forwardWhat is the result of the following gram stain: positive ○ capsulated ○ acid-fast ○ negativearrow_forwardWhat type of stain is the image below: capsule stain endospore stain gram stain negative stain ASM MicrobeLibrary.org Keplingerarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage LearningConcepts of BiologyBiologyISBN:9781938168116Author:Samantha Fowler, Rebecca Roush, James WisePublisher:OpenStax College
- Human Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage LearningAnatomy & PhysiologyBiologyISBN:9781938168130Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark WomblePublisher:OpenStax College
Human Physiology: From Cells to Systems (MindTap ...
Biology
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Cengage Learning
Concepts of Biology
Biology
ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:OpenStax College
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
Anatomy & Physiology
Biology
ISBN:9781938168130
Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble
Publisher:OpenStax College