NESTER'S MICROBIOLOGY: A HUMAN PERSPECT
9th Edition
ISBN: 9781260161373
Author: Anderson, SALM
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Chapter 17, Problem 5SA
Summary Introduction
To review:
The cause of HDN (hemolytic disease of the newborn).
Introduction:
HDN is also referred to as hemolytic disease, which is considered to be an alloimmune state that grows in a peripartum fetus. This occurs when the IgG molecules are generated by the mother cross the placenta and enter the fetus blood. In simpler words, it means that the condition arises when there is an incompatibility present among the blood type of the fetus and the mother.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 17 Solutions
NESTER'S MICROBIOLOGY: A HUMAN PERSPECT
Ch. 17 - Prob. 1SACh. 17 -
2. List two physical responses of systemic...Ch. 17 - What are the major differences between an...Ch. 17 - Compare and contrast the Arthus reaction and serum...Ch. 17 - Prob. 5SACh. 17 - Compare and contrast the autoimmune processes...Ch. 17 -
7. Give an example of an organ-specific...Ch. 17 - Explain why a patient who received a successful...Ch. 17 - Why does an IgA deficiency predispose a person to...Ch. 17 - What is the difference between a primary...
Ch. 17 - Prob. 1MCCh. 17 - Prob. 2MCCh. 17 - Prob. 3MCCh. 17 - Prob. 4MCCh. 17 - Delayed-type hypersensitivity reactions in the...Ch. 17 - Prob. 6MCCh. 17 - Prob. 7MCCh. 17 - Prob. 8MCCh. 17 - Prob. 9MCCh. 17 - Prob. 10MCCh. 17 - Jack and Jill were badly burned in an accident at...Ch. 17 - Horse serum containing specific antibody to snake...Ch. 17 - Hypersensitivity reactions, by definition, lead to...Ch. 17 - Prob. 2CT
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