Chapter 17, Problem 3EQ

Summary Introduction

To review:

The way double-stranded RNA proposed by Fire and Mello is potent at silencing mex-3 (muscle excess 3)mRNA(messenger ribonucleic acid).

Introduction:

Researchers often introduced antisense and sense RNA into cells to inhibit mRNA translation. Specific mRNAs can be targeted for translational inhibition by double-stranded RNA mechanism. For this, Caenorhabditiselegans was used because of the ease of injection of RNA and the expression of many of its genes was already established.