Concepts of Biology
1st Edition
ISBN: 9781938168116
Author: Samantha Fowler, Rebecca Roush, James Wise
Publisher: OpenStax College
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Chapter 17, Problem 18CTQ
Different MHC class I molecules between donor and recipient cells can lead to rejection of a transplanted organ or tissue. Suggest a reason for this.
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Different MHC I molecules between donor and recipient cells can lead to rejection of a transplanted organ or tissue. Explain relevant concepts in relation to tissue rejection in organ transplant.
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Chapter 17 Solutions
Concepts of Biology
Ch. 17 - Figure 17.5 Which of the following statements...Ch. 17 - Figure 17.6 Influenza virus is packaged in a viral...Ch. 17 - Figure 17.17 The Rh antigen is found on...Ch. 17 - Which statement is true? a. A virion contains DNA...Ch. 17 - The viral ________ plays a role in attaching a...Ch. 17 - Which statement is true of viral replication? a....Ch. 17 - Which of the following is a barrier against...Ch. 17 - Although interferons have several effects, they...Ch. 17 - Which innate immune system component uses MHC...Ch. 17 - The humoral immune response depends on which...
Ch. 17 - The fact that the body does not normally mount an...Ch. 17 - Foreign particles circulating in the blood are...Ch. 17 - Allergy to pollen is classified as _______. a. an...Ch. 17 - A potential cause of acquired autoimmunity is...Ch. 17 - Autoantibodies are probably involved in ________....Ch. 17 - Why can’t dogs catch the measles?Ch. 17 - Why is immunization after being bitten by a rabid...Ch. 17 - Different MHC class I molecules between donor and...Ch. 17 - If a series of genetic mutations prevented some,...Ch. 17 - How do B and T cells differ with respect to...Ch. 17 - Why is the immune response after reinfection much...Ch. 17 - Some photographers develop a sensitivity to...
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- why is MALT considered strategically placed?arrow_forwardCancer cells often underexpress MHC class 1 molecules. Due to these characteristics, they may be the target of: B cells Eosinophils Neutrophils NK cells OMacrophagesarrow_forwardPeptide editing is an important component of antigen presentation for both MHC class I and MHC class II pathways, as it drives the preferential presentation of high-affinity binding peptides. For MHC class II peptide editing, HLA-DM plays a key role. In the absence of HLA-DM: MHC class II molecules traffic to the cell surface with CLIP in their binding sites. No MHC class II molecules are released to traffic to the cell surface. MHC class II molecules bind to HLA-DO and are inhibited from binding peptides. Pathogens can evade the immune system by blocking peptide exchange on MHC class II. HLA-DO competes for high-affinity binding peptides with MHC class II molecules and blocks antigen presentation.arrow_forward
- A 39-year-old woman with rheumatoid arthritis comes to the physician for a follow-up examination. Treatment with multiple medications, including prednisone and methotrexate, has not been effective at slowing the progress of her condition. The most appropriate next step in pharmacotherapy is a drug that blocks the effects of which of the following cytokines? Entaracept : Fusion protein- decoy receptor A) Interferon gamma B) Interleukin-2 (IL-2) C) IL-4 D) IL-10 E) Tumor necrosis factor-a foundarrow_forwardExplain the term immunoglobulin (IG).arrow_forwardDiscuss the involvement of T cells in organ transplantation and thedifferent ways that grafted tissues may be rejected.arrow_forward
- Name two ways in which the presence of antibodies enhances phagocytosis.arrow_forwardList the steps of MHC class I peptide formation and assembly.arrow_forwardNeutralizing antibodies are effective at preventing infection or toxicity mediated by pathogens or their toxic products. In fact, nearly all vaccines currently in use function by eliciting neutralizing antibodies. One example is the tetanus vaccine, in which neutralizing antibodies are generated against an inactivated form of the tetanus toxin (the tetanus toxoid). The most important feature of a neutralizing antibody is having high affinity for the antigen. being efficient at activating the complement cascade. having a high degree of multivalency, such as being a pentamer or hexamer of immunoglobulin monomers. being present at a high concentration in the circulation. 0 0 0 0arrow_forward
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