Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
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Chapter 17, Problem 17E
Summary Introduction
To determine: .Why a deficiency of pyruvate carboxylase leads to lactic acidosis.
Concept introduction: Citric acid cycle is the major source of free energy and its intermediates must be in adequate quantity to run without interruption. Pyruvate carboxylase converts pyruvate into oxaloacetate, which is used in the citric acid cycle.
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Chapter 17 Solutions
Fundamentals of Biochemistry: Life at the Molecular Level
Ch. 17 - Prob. 1ECh. 17 - 2. If acetyl-CoA is labeled with l4C at its methyl...Ch. 17 - 3. List four possible metabolic fates for pyruvate...Ch. 17 - 4. Explain why metabolic acidosis (Box 2-2) may...Ch. 17 - 5. Which one of the live steps of the pyruvate...Ch. 17 - Prob. 6ECh. 17 - 7. Photosynthetic organisms use elaborate...Ch. 17 - 6. Does the pyruvate-formate lyase reaction...Ch. 17 - Prob. 9ECh. 17 - Prob. 10E
Ch. 17 - Prob. 11ECh. 17 - 12. What citric acid cycle intermediates would...Ch. 17 - Prob. 13ECh. 17 - Prob. 14ECh. 17 - Prob. 15ECh. 17 - 16. What is the ratio of [isocitrate] to [citrate]...Ch. 17 - 17. Explain why a deficiency of pyruvate...Ch. 17 - Prob. 18ECh. 17 - Prob. 19ECh. 17 - Prob. 20ECh. 17 - 21. Helicobacter pylori, which causes gastric...Ch. 17 - Prob. 22ECh. 17 - Prob. 23CQCh. 17 - 24. Which compounds would accumulate in an...Ch. 17 - Prob. 25CQCh. 17 - 26. Certain microorganisms with an incomplete...Ch. 17 - Prob. 27CQCh. 17 - Prob. 28CQCh. 17 - Prob. 29CQCh. 17 - Prob. 30CQCh. 17 - 31. Anaplerotic reactions permit the citric acid...Ch. 17 - 32. Although animals cannot synthesize glucose...Ch. 17 - Prob. 33CQCh. 17 - Prob. 34CQCh. 17 - Prob. 35CQCh. 17 - 36. Acetyl-CoA, in addition to providing 2-carbon...Ch. 17 - Prob. 1MTE
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