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Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
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Chapter 17, Problem 27CQ
Summary Introduction
To explain: The inhibition of phosphofructokinase is advantageous for citrate.
Concept introduction: Citrate is the allosteric inhibitor of phosphofructokinase. It inactivates phosphofructokinase when its concentration is high, but not when citrate concentration is low.
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Chapter 17 Solutions
Fundamentals of Biochemistry: Life at the Molecular Level
Ch. 17 - Prob. 1ECh. 17 - 2. If acetyl-CoA is labeled with l4C at its methyl...Ch. 17 - 3. List four possible metabolic fates for pyruvate...Ch. 17 - 4. Explain why metabolic acidosis (Box 2-2) may...Ch. 17 - 5. Which one of the live steps of the pyruvate...Ch. 17 - Prob. 6ECh. 17 - 7. Photosynthetic organisms use elaborate...Ch. 17 - 6. Does the pyruvate-formate lyase reaction...Ch. 17 - Prob. 9ECh. 17 - Prob. 10E
Ch. 17 - Prob. 11ECh. 17 - 12. What citric acid cycle intermediates would...Ch. 17 - Prob. 13ECh. 17 - Prob. 14ECh. 17 - Prob. 15ECh. 17 - 16. What is the ratio of [isocitrate] to [citrate]...Ch. 17 - 17. Explain why a deficiency of pyruvate...Ch. 17 - Prob. 18ECh. 17 - Prob. 19ECh. 17 - Prob. 20ECh. 17 - 21. Helicobacter pylori, which causes gastric...Ch. 17 - Prob. 22ECh. 17 - Prob. 23CQCh. 17 - 24. Which compounds would accumulate in an...Ch. 17 - Prob. 25CQCh. 17 - 26. Certain microorganisms with an incomplete...Ch. 17 - Prob. 27CQCh. 17 - Prob. 28CQCh. 17 - Prob. 29CQCh. 17 - Prob. 30CQCh. 17 - 31. Anaplerotic reactions permit the citric acid...Ch. 17 - 32. Although animals cannot synthesize glucose...Ch. 17 - Prob. 33CQCh. 17 - Prob. 34CQCh. 17 - Prob. 35CQCh. 17 - 36. Acetyl-CoA, in addition to providing 2-carbon...Ch. 17 - Prob. 1MTE
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- 17. Which one of the compounds below is the major organic product obtained from the following series of reactions? CI benzyl alcohol OH PBr3 Mg 1. CO2 SOCl2 ? ether 2. H+, H₂O CI Cl HO OH CI Cl A B C D Earrow_forward14. What is the IUPAC name of this compound? A) 6-hydroxy-4-oxohexanenitrile B) 5-cyano-3-oxo-1-pentanol C) 5-cyano-1-hydroxy-3-pentanone D) 1-cyano-5-hydroxy-3-pentanone E) 5-hydroxy-3-oxopentanenitrile HO. CNarrow_forward13. What is the IUPAC name of this compound? A) 5-hydroxy-3,3-dimethylpentanoic acid B) 3,3-dimethylpentanoic acid C) 3,3-dimethyl-1-oxo-1,5-pentanediol D) 1,5-dihydroxy-3,3-dimethylpentanal E) 4-hydroxy-2,2-dimethylbutanoic acid HO OHarrow_forward
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- An ATP-coupled transporter is used to import 1 phosphate from the extracellular environment. Intracellular phosphate exists at 65mM, while it is 2mM outside.Assume a free energy change of ATP hydrolysis of -42.7 kJ/mol. What is the net free energy change of the coupled reaction? Assume a membrane potential of 70mV.arrow_forwardAnother transporter brings 3 chloride ions into the cell. Outside, chloride has a concentration of 107mM, and 4mM inside the cell. Assuming a membrane potential of 62mV (negative inside), what is the free energy of transport of these ions?arrow_forwardFor the Oxaloacetate -> Malate reaction, assume the normal ratio of NAD/NADH, what is the maximum ratio of Malate/Oxaloacetate that will allow reaction progress?arrow_forward
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