The advantages of arranging the enzymes which catalyze the synthesis of the acetyl CoA from pyruvate into a single large complex. Concept introduction: Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. The five enzymes which form the pyruvate dehydrogenase complex are pyruvate dehydrogenase, dihydrolipoyl dehydrogenase, Kinase, dihydrolipoyl transacetylase, and phosphatase. It helps in the conversion of pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

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Chapter 17, Problem 11P

Interpretation Introduction

Interpretation:

The advantages of arranging the enzymes which catalyze the synthesis of the acetyl CoA from pyruvate into a single large complex.

Concept introduction:

Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. The five enzymes which form the pyruvate dehydrogenase complex are pyruvate dehydrogenase, dihydrolipoyl dehydrogenase, Kinase, dihydrolipoyl transacetylase, and phosphatase. It helps in the conversion of pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.

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