a) Interpretation: The flaw in the synthesis given is to be stated. Concept introduction: In aromatic electrophilic substitution reactions, alkyl groups are ortho and para directing and activating groups while carboxylic acid group are meta directing and deactivating group. While oxidizing with KMnO 4 the alkyl groups in the side chain are oxidized and the aromatic ring remains unaffected. To state: The flaw in the synthesis given.
a) Interpretation: The flaw in the synthesis given is to be stated. Concept introduction: In aromatic electrophilic substitution reactions, alkyl groups are ortho and para directing and activating groups while carboxylic acid group are meta directing and deactivating group. While oxidizing with KMnO 4 the alkyl groups in the side chain are oxidized and the aromatic ring remains unaffected. To state: The flaw in the synthesis given.
Solution Summary: The author explains that in aromatic electrophilic substitution reactions, alkyl groups are ortho and para directing and activating groups.
Study of body parts and their functions. In this combined field of study, anatomy refers to studying the body structure of organisms, whereas physiology refers to their function.
Chapter 16.SE, Problem 58AP
Interpretation Introduction
a)
Interpretation:
The flaw in the synthesis given is to be stated.
Concept introduction:
In aromatic electrophilic substitution reactions, alkyl groups are ortho and para directing and activating groups while carboxylic acid group are meta directing and deactivating group. While oxidizing with KMnO4 the alkyl groups in the side chain are oxidized and the aromatic ring remains unaffected.
To state:
The flaw in the synthesis given.
Interpretation Introduction
b)
Interpretation:
The flaw in the synthesis given is to be stated.
Concept introduction:
In aromatic electrophilic substitution reactions, halogens are ortho and para directing groups. Friedal-Crafts alkylation is not possible with aromatic compounds with a deactivating group like NO2 etc. attached to the ring.
To state:
The flaw in the synthesis given.
Interpretation Introduction
c)
Interpretation:
The flaw in the synthesis given is to be stated.
Concept introduction:
In aromatic electrophilic substitution reactions, alkyl groups are ortho and para directing and activating groups while carbonyl group is a meta directing and deactivating group. When treated with H2/Pd the –C=O group gets reduced to –CH2 group and –NO2 gets reduced to –NH2 group.
