MICROBIOLOGY FUND.:CLINICAL APPR-ACCESS
3rd Edition
ISBN: 2810022612789
Author: Cowan
Publisher: MCG
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Chapter 16, Problem 6Q
Summary Introduction
To determine:
The pyogenic nature of Staphylococcus aureus, and Streptococcus pyogenic, and also determine the attributes of the two bacteria are likely to contribute to that phenomena.
Concept introduction
Impetigo is also known as pyoderma (Pyon means pus and derma mean skin), which is caused by two different types of bacteria. It is a contagious disease which is characterized by the development of flattened, small, red patches on the skin and limbs. These patches contain pus-filled, oozing vesicles on a red base. On the broken down of these vesicles, thick honey-colored sticky liquid ooze out that firmly attached to the skin and cause intense itching.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 16 Solutions
MICROBIOLOGY FUND.:CLINICAL APPR-ACCESS
Ch. 16.1 - Describe the important anatomical features of the...Ch. 16.1 - Prob. 2AYPCh. 16.1 - Prob. 1NPCh. 16.2 - Prob. 3AYPCh. 16.3 - Prob. 4AYPCh. 16.3 - Prob. 5AYPCh. 16.3 - Prob. 6AYPCh. 16.3 - Prob. 7AYPCh. 16.3 - Prob. 2NPCh. 16.3 - Prob. 3NP
Ch. 16.3 - Prob. 1MMCh. 16.3 - Prob. 2MMCh. 16.3 - Prob. 4NPCh. 16.4 - Prob. 8AYPCh. 16.4 - Prob. 9AYPCh. 16.5 - List the types of normal biota presently known to...Ch. 16.6 - Prob. 11AYPCh. 16.6 - Prob. 12AYPCh. 16.6 - Prob. 5NPCh. 16 - Prob. 1QCh. 16 - Can you think of a plausible argument for why...Ch. 16 - Prob. 3QCh. 16 - Prob. 4QCh. 16 - What cell structure of Bacillus anthracis makes it...Ch. 16 - Prob. 6QCh. 16 - Which of the following organisms produces an...Ch. 16 - Prob. 8QCh. 16 - Prob. 9QCh. 16 - Prob. 10QCh. 16 - Prob. 11QCh. 16 - Prob. 12QCh. 16 - Which of the following conditions is most likely...Ch. 16 - Prob. 14QCh. 16 - Prob. 15QCh. 16 - Prob. 16QCh. 16 - Prob. 17QCh. 16 - Prob. 18QCh. 16 - Prob. 19QCh. 16 - Explain why detecting a single case of smallpox...Ch. 16 - Prob. 21QCh. 16 - From chapter 11, figure 11.2. How does this figure...
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