Microbiology with Diseases by Body System (4th Edition)
4th Edition
ISBN: 9780321918550
Author: Robert W. Bauman Ph.D.
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Textbook Question
Chapter 16, Problem 3TMW
Why did scientists give the name perforin to a molecule secreted by Tc cells?
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Use the following choices for the next set of questions. A choice may be used zero or more times:
a)CD4
b) CD8
c) lg
d) TCR
e) More than one of these
26) Found on the cell surface
27) Expressed by T helper cells as a co-receptor
28) Expressed by B lymphocytes
29) Associated with cell that produces perforin
30) Composed of heavy and light chain
31) Capable of recognizing a carbohydrate antigen
32) Has effector functions
Which of the following is false when considering the CCR5Δ32 mutation?
a) The mutation prevents the entry of HIV-1 into a T cell.
b) The deletion that produced CCR5Δ32 caused a frameshift which extends the length of the protein product.
c) CCR5Δ32 prevents infection by HIV-1 in homozygotes but only delays the onset of HIV symptoms in heterozygotes.
d) The protein product produced by CCR5Δ32 is altered in such a manner that it cannot embed in the cell membrane.
Use the following choices for the next set of questions. A choice may be used zero or more times:
a)MHC class I
b) MHC class Il
C) both MHC class I and II
d) neither MHC class | or II
e) cannot be determined
21) expressed on T cells
22) captures antigens present in endosomes
23) strongly affected by proteasomal inhibition
24) downregulated by many viruses
25) the genes responsible for expression are monomorphic, meaning that identical alleles are shared throughout the population
Chapter 16 Solutions
Microbiology with Diseases by Body System (4th Edition)
Ch. 16 - Why are the activities of B and T cells called...Ch. 16 - Why are exogenous epitopes processed in vesicles...Ch. 16 - Why did scientists give the name perforin to a...Ch. 16 - Plasma cells are vital for protection against...Ch. 16 - Microsporidiosis Darius is sick, which is not...Ch. 16 - Why is passive immunity effective more quickly...Ch. 16 - Prob. 1MCCh. 16 - Prob. 2MCCh. 16 - Rejection of a foreign skin graft is an example of...Ch. 16 - An autoantigen is ________________. a. an antigen...
Ch. 16 - Among the key molecules that control cell-mediated...Ch. 16 - Which of the following lymphocytes predominates in...Ch. 16 - Prob. 7MCCh. 16 - Which cells express MHC class I molecules in a...Ch. 16 - In which of the following sites in the body can B...Ch. 16 - Tc cells recognize epitopes only when the latter...Ch. 16 - Prob. 1MTFCh. 16 - Prob. 2MTFCh. 16 - Prob. 3MTFCh. 16 - Prob. 4MTFCh. 16 - Prob. 5MTFCh. 16 - Match each cell in the left column with its...Ch. 16 - Match each type of immunity in the left column...Ch. 16 - Label the parts of the immunoglobulin below.Ch. 16 - The nearby image is a transmission electron...Ch. 16 - When is antigen processing an essential...Ch. 16 - Why does the body have both antibody and...Ch. 16 - Why is it advantageous for the lymphatic system to...Ch. 16 - Contrast innate defenses with adaptive immunity.Ch. 16 - How does requiring the immune system to process...Ch. 16 - Scientists can develop genetically deficient...Ch. 16 - Human immunodeficiency virus (HIV) preferentially...Ch. 16 - What would happen to a person who failed to make...Ch. 16 - Prob. 7CTCh. 16 - Some materials, such as metal bone pins and...Ch. 16 - Prob. 9CTCh. 16 - The cross-sectional area of the afferent lymphatic...Ch. 16 - Two students are studying for an exam on the bodys...Ch. 16 - In general, what sorts of pathogens might be able...Ch. 16 - What sorts of pathogens could successfully attack...Ch. 16 - As part of the treatment for some cancers,...Ch. 16 - Prob. 1CM
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- The p75 receptor differs from Trk receptors in that it a) can promote cell death. b) has high affinity for all neurotrophins. c) only binds a particular type of neurotrophin. d) can bind NGF to promote cell survival.arrow_forwardTypical symptoms of COVID-19 include: (1) fever (83-98%), (2) cough (46-82%), (3) muscle pain or fatigue (11-44%), (4) shortness of breath (31%), and in some severe cases, (5) acute respiratory failure, (6) secondary infection and (7) interferon gamma-related cytokine storm. Pick 3 of the above symptoms, and explain why the patients may have these symptoms.arrow_forwardBeta- lactam drugs by inhibiting formation of the plasma membrane. a) true b) falsearrow_forward
- Synaptic vesicles release into the synapse to give the message to the post synaptic neuron?Multicellular organisms:a) are larger in size than unicellular organisms b) can do a wider variety of functionsFor a stroke patient with hypertension who is a candidate for recombinant tissue plasminogen activator rt pa which blood pressure control strategy is appropriate?arrow_forwardPoliovirus is highly cytopathic both in cultured cells and in animals. Inoculation of mice with poliovirus leads to a robust antibody and cellular response. Explain why mice infected with a poliovirus mutant that cannot cause cell death have poor antibody and cellular responses. What would be one strategy to restore robust antibody and cellular responses in mice infected with this mutant virus?arrow_forwarda) What is the main structural and functional difference between microbial opsins and mammalian opsins? b) Give one example to each group. c) Why does the discovery of those microbial opsins become a major breakthrough in neuroscience? Edit Format Tablearrow_forward
- Why would attaching an enediyne- containing molecule to an antibody be an attractive way to treat cancer cells?arrow_forwardThe Fab regions of an antibody are made of which protein chain? A) a heavy chain containing only constant regions B) a light chain containing variable and constant regions C) a heavy chain containing variable and constant regions D) both a light chain and a heavy chain containing variable and constant regions E) both a light chain containing variable and constant regions and a heavy chain containing only constant regionsarrow_forwardCTLs use the following membrane-bound protein interactions to “kill” a target cell through apoptosis: Question 8 options: A) IL-2/IL-2 receptor B) CD4/MHC II C) TCR/MHC II D) Fas/FasLarrow_forward
- Which of the conformations illustrated above (a or b) is more likely PrPc (the normal cellular form of PrP) and which is more likely PrPSc (the pathogenic form of PrP)? Why?arrow_forwardWhich example would benefit most from the use of pluripotent stem cells made from the patient's own cells? A) An autoimmune disease, inappropriate targeting of the patient's immune system, destroyed a patient's thyroid gland B) A neurodegenerative disease, abnormal cell death of brain cells, destroyed a specific region of the patient's brain C) A patient suffered severe burns over much of their legs and feet D) A person with a congenital disease has been blind from birth.arrow_forwardExperiments are performed to analyze protein tyrosine phosphorylation in response to TCR stimulation. For these experiments, T cells are stimulated with anti-CD3 antibody, and then lysates are prepared and run on a protein (SDS-PAGE) gel to separate the proteins by molecular weight. The proteins are transferred from the gel to a membrane for immunoblotting using an antibody that binds to all phosphorylated tyrosine residues in any protein; this antibody is called ‘anti-phospho-tyrosine antibody,’ and is abbreviated as anti-P-Y. The results are shown in the figure below. You confirm that the mutant T cells express normal levels of all the proteins detected in the WT cells, including PLC-g, SLP-76, ITK, ZAP-70, LCK, LAT, and the CD3 and TCRz proteins. Based on these data, which of the following proteins (biotin, hygromycin, and streptavidin) can rule out its presence? Briefly explain your answer. What protein is most likely defective in the mutant cells and why? For the protein you…arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
Immune System and Immune Response Animation; Author: Medical Sciences Animations;https://www.youtube.com/watch?v=JDdbUBXPKc4;License: Standard YouTube License, CC-BY
Immune response: summary; Author: Dr Bhavsar Biology;https://www.youtube.com/watch?v=ADANgHkX4OY;License: Standard Youtube License