
Concept explainers
70-Year-Old Male with Polyuria
Mr. Gutteman, a 70-year-old male, was brought into the ER. He had been sick several days with the flu, and was found confused and barely conscious by his daughter.
Mr. Gutteman is breathing rapidly and has a fever of 39°C (102°F). His skin is dry and flaccid, his mucous membranes are dry, and his eyes are sunken. The physician ordered:
•IV (intravenous) fluid and electrolyte replacement
•Blood and urine tests for presence of glucose and
•Strict I&O [careful measurement of fluid intake (e.g., IV, drinking) and output (e.g., urine)]
3. Mr. Gutteman's diagnosis is diabetes insipidus. His daughter is concerned about this, because she knows diabetes is a dangerous disease. She asks whether he will have to follow a diabetic diet. What’s your answer?

Want to see the full answer?
Check out a sample textbook solution
Chapter 16 Solutions
Human Anatomy & Physiology Plus Modified Mastering A&P with Pearson eText -- Access Card Package 11th edition
- The following table is from Kumar et. al. Highly Selective Dopamine D3 Receptor (DR) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment. J. Med Chem 2016.arrow_forwardThe following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. You are a chef in a fancy new science-themed restaurant. You have a recipe that calls for 1 teaspoon of resinferatoxin, but you feel uncomfortable serving foods with "toxins" in them. How much capsaicin could you substitute instead?arrow_forwardWhat protein is necessary for packaging acetylcholine into synaptic vesicles?arrow_forward
- 1. Match each vocabulary term to its best descriptor A. affinity B. efficacy C. inert D. mimic E. how drugs move through body F. how drugs bind Kd Bmax Agonist Antagonist Pharmacokinetics Pharmacodynamicsarrow_forward50 mg dose of a drug is given orally to a patient. The bioavailability of the drug is 0.2. What is the volume of distribution of the drug if the plasma concentration is 1 mg/L? Be sure to provide units.arrow_forwardDetermine Kd and Bmax from the following Scatchard plot. Make sure to include units.arrow_forward
- Choose a catecholamine neurotransmitter and describe/draw the components of the synapse important for its signaling including synthesis, packaging into vesicles, receptors, transporters/degradative enzymes. Describe 2 drugs that can act on this system.arrow_forwardThe following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. a) Which has a higher potency? b) Which is has a higher efficacy? c) What is the approximate Kd of capsaicin in uM? (you can round to the nearest power of 10)arrow_forwardWhat is the rate-limiting-step for serotonin synthesis?arrow_forward
- Essentials of Pharmacology for Health ProfessionsNursingISBN:9781305441620Author:WOODROWPublisher:Cengage
- Anatomy & PhysiologyBiologyISBN:9781938168130Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark WomblePublisher:OpenStax College
