How the activity of the citrate synthase is regulated by succinyl CoA, on the basis of the graph given. Introduction : Citrate synthase is found in almost all the living cells. This enzyme functions as the catalyst in the citric acid cycle. Citric acid is found in mitochondrial matrix of eukaryotic cells but it is not encoded by mitochondrial DNA instead it is encoded by nuclear DNA. Succinyl CoA resembles acetyl CoA in structure and it inhibits the activity of the enzyme citric acid synthase.

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Answer 1

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Definition Definition Set of metabolic processes and reactions that produce energy from organic substances such as glucose. Cellular respiration takes place in the organism’s cells, where the chemical energy from nutrients or molecules of oxygen is converted into adenosine triphosphate (ATP). Cellular respiration that occurs in the presence of oxygen is called aerobic respiration; in the absence of oxygen, it is called anaerobic respiration.

Chapter 16, Problem 28P

Summary Introduction

To explain: How the activity of the citrate synthase is regulated by succinyl CoA, on the basis of the graph given.

Introduction:

Citrate synthase is found in almost all the living cells. This enzyme functions as the catalyst in the citric acid cycle. Citric acid is found in mitochondrial matrix of eukaryotic cells but it is not encoded by mitochondrial DNA instead it is encoded by nuclear DNA. Succinyl CoA resembles acetyl CoA in structure and it inhibits the activity of the enzyme citric acid synthase.

Summary Introduction

To explain: Why succinyl CoA is a suitable indicator for the regulation of citric acid cycle.

Introduction:

Succinyl CoA is a competitive inhibitor of acetyl CoA. Acetyl CoA is responsible for the activity of the enzyme citrate synthase. Increased concentration of succinyl CoA decreases the amount of acetyl CoA, hence activity of citrate synthase is regulated.

Summary Introduction

To explain: How the rate of cellular respiration in pig heart tissue is controlled by regulation of citrate synthase.

Introduction:

Citric acid cycle is a type of cellular respiration which takes place in the mitochondrial matrix. Citric acid cycle is an aerobic cellular respiration which requires oxygen for proper functioning.

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The rate data from an enzyme catalyzed reaction with and without an inhibitor present is found in the image. Question: what is the KM and Vm and the nature of inhibition

1. Estimate the concentration of an enzyme within a living cell. Assume that: (a): fresh tissue is 80% water and all of it is intracellular (b): the total soluble protein represents 15% of the weight (c): all the soluble proteins are enzymes (d): the average molecular weight of the proteins is 150,000 (E): about 100 different enzymes are present please help I am lost

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Answer 2

Question

Definition Definition Set of metabolic processes and reactions that produce energy from organic substances such as glucose. Cellular respiration takes place in the organism’s cells, where the chemical energy from nutrients or molecules of oxygen is converted into adenosine triphosphate (ATP). Cellular respiration that occurs in the presence of oxygen is called aerobic respiration; in the absence of oxygen, it is called anaerobic respiration.

Chapter 16, Problem 28P

Summary Introduction

To explain: How the activity of the citrate synthase is regulated by succinyl CoA, on the basis of the graph given.

Introduction:

Citrate synthase is found in almost all the living cells. This enzyme functions as the catalyst in the citric acid cycle. Citric acid is found in mitochondrial matrix of eukaryotic cells but it is not encoded by mitochondrial DNA instead it is encoded by nuclear DNA. Succinyl CoA resembles acetyl CoA in structure and it inhibits the activity of the enzyme citric acid synthase.

Summary Introduction

To explain: Why succinyl CoA is a suitable indicator for the regulation of citric acid cycle.

Introduction:

Succinyl CoA is a competitive inhibitor of acetyl CoA. Acetyl CoA is responsible for the activity of the enzyme citrate synthase. Increased concentration of succinyl CoA decreases the amount of acetyl CoA, hence activity of citrate synthase is regulated.

Summary Introduction

To explain: How the rate of cellular respiration in pig heart tissue is controlled by regulation of citrate synthase.

Introduction:

Citric acid cycle is a type of cellular respiration which takes place in the mitochondrial matrix. Citric acid cycle is an aerobic cellular respiration which requires oxygen for proper functioning.

Expert Solution & Answer

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See solution

Answer 3

Question

Definition Definition Set of metabolic processes and reactions that produce energy from organic substances such as glucose. Cellular respiration takes place in the organism’s cells, where the chemical energy from nutrients or molecules of oxygen is converted into adenosine triphosphate (ATP). Cellular respiration that occurs in the presence of oxygen is called aerobic respiration; in the absence of oxygen, it is called anaerobic respiration.

Chapter 16, Problem 28P

Summary Introduction

To explain: How the activity of the citrate synthase is regulated by succinyl CoA, on the basis of the graph given.

Introduction:

Citrate synthase is found in almost all the living cells. This enzyme functions as the catalyst in the citric acid cycle. Citric acid is found in mitochondrial matrix of eukaryotic cells but it is not encoded by mitochondrial DNA instead it is encoded by nuclear DNA. Succinyl CoA resembles acetyl CoA in structure and it inhibits the activity of the enzyme citric acid synthase.

Summary Introduction

To explain: Why succinyl CoA is a suitable indicator for the regulation of citric acid cycle.

Introduction:

Succinyl CoA is a competitive inhibitor of acetyl CoA. Acetyl CoA is responsible for the activity of the enzyme citrate synthase. Increased concentration of succinyl CoA decreases the amount of acetyl CoA, hence activity of citrate synthase is regulated.

Summary Introduction

To explain: How the rate of cellular respiration in pig heart tissue is controlled by regulation of citrate synthase.

Introduction:

Citric acid cycle is a type of cellular respiration which takes place in the mitochondrial matrix. Citric acid cycle is an aerobic cellular respiration which requires oxygen for proper functioning.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Set of metabolic processes and reactions that produce energy from organic substances such as glucose. Cellular respiration takes place in the organism’s cells, where the chemical energy from nutrients or molecules of oxygen is converted into adenosine triphosphate (ATP). Cellular respiration that occurs in the presence of oxygen is called aerobic respiration; in the absence of oxygen, it is called anaerobic respiration.

Chapter 16, Problem 28P

Summary Introduction

To explain: How the activity of the citrate synthase is regulated by succinyl CoA, on the basis of the graph given.

Introduction:

Citrate synthase is found in almost all the living cells. This enzyme functions as the catalyst in the citric acid cycle. Citric acid is found in mitochondrial matrix of eukaryotic cells but it is not encoded by mitochondrial DNA instead it is encoded by nuclear DNA. Succinyl CoA resembles acetyl CoA in structure and it inhibits the activity of the enzyme citric acid synthase.

Summary Introduction

To explain: Why succinyl CoA is a suitable indicator for the regulation of citric acid cycle.

Introduction:

Succinyl CoA is a competitive inhibitor of acetyl CoA. Acetyl CoA is responsible for the activity of the enzyme citrate synthase. Increased concentration of succinyl CoA decreases the amount of acetyl CoA, hence activity of citrate synthase is regulated.

Summary Introduction

To explain: How the rate of cellular respiration in pig heart tissue is controlled by regulation of citrate synthase.

Introduction:

Citric acid cycle is a type of cellular respiration which takes place in the mitochondrial matrix. Citric acid cycle is an aerobic cellular respiration which requires oxygen for proper functioning.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 5

Chapter 16, Problem 28P

Summary Introduction

To explain: How the activity of the citrate synthase is regulated by succinyl CoA, on the basis of the graph given.

Introduction:

Citrate synthase is found in almost all the living cells. This enzyme functions as the catalyst in the citric acid cycle. Citric acid is found in mitochondrial matrix of eukaryotic cells but it is not encoded by mitochondrial DNA instead it is encoded by nuclear DNA. Succinyl CoA resembles acetyl CoA in structure and it inhibits the activity of the enzyme citric acid synthase.

Summary Introduction

To explain: Why succinyl CoA is a suitable indicator for the regulation of citric acid cycle.

Introduction:

Succinyl CoA is a competitive inhibitor of acetyl CoA. Acetyl CoA is responsible for the activity of the enzyme citrate synthase. Increased concentration of succinyl CoA decreases the amount of acetyl CoA, hence activity of citrate synthase is regulated.

Summary Introduction

To explain: How the rate of cellular respiration in pig heart tissue is controlled by regulation of citrate synthase.

Introduction:

Citric acid cycle is a type of cellular respiration which takes place in the mitochondrial matrix. Citric acid cycle is an aerobic cellular respiration which requires oxygen for proper functioning.

Answer 6

Chapter 16, Problem 28P

Summary Introduction

To explain: How the activity of the citrate synthase is regulated by succinyl CoA, on the basis of the graph given.

Introduction:

Citrate synthase is found in almost all the living cells. This enzyme functions as the catalyst in the citric acid cycle. Citric acid is found in mitochondrial matrix of eukaryotic cells but it is not encoded by mitochondrial DNA instead it is encoded by nuclear DNA. Succinyl CoA resembles acetyl CoA in structure and it inhibits the activity of the enzyme citric acid synthase.

Answer 7

Chapter 16, Problem 28P

Summary Introduction

To explain: How the activity of the citrate synthase is regulated by succinyl CoA, on the basis of the graph given.

Introduction:

Citrate synthase is found in almost all the living cells. This enzyme functions as the catalyst in the citric acid cycle. Citric acid is found in mitochondrial matrix of eukaryotic cells but it is not encoded by mitochondrial DNA instead it is encoded by nuclear DNA. Succinyl CoA resembles acetyl CoA in structure and it inhibits the activity of the enzyme citric acid synthase.

Answer 8

Summary Introduction

To explain: Why succinyl CoA is a suitable indicator for the regulation of citric acid cycle.

Introduction:

Succinyl CoA is a competitive inhibitor of acetyl CoA. Acetyl CoA is responsible for the activity of the enzyme citrate synthase. Increased concentration of succinyl CoA decreases the amount of acetyl CoA, hence activity of citrate synthase is regulated.

Answer 9

Summary Introduction

To explain: Why succinyl CoA is a suitable indicator for the regulation of citric acid cycle.

Introduction:

Succinyl CoA is a competitive inhibitor of acetyl CoA. Acetyl CoA is responsible for the activity of the enzyme citrate synthase. Increased concentration of succinyl CoA decreases the amount of acetyl CoA, hence activity of citrate synthase is regulated.

Answer 10

Summary Introduction

To explain: How the rate of cellular respiration in pig heart tissue is controlled by regulation of citrate synthase.

Introduction:

Citric acid cycle is a type of cellular respiration which takes place in the mitochondrial matrix. Citric acid cycle is an aerobic cellular respiration which requires oxygen for proper functioning.

Answer 11

Summary Introduction

To explain: How the rate of cellular respiration in pig heart tissue is controlled by regulation of citrate synthase.

Introduction:

Citric acid cycle is a type of cellular respiration which takes place in the mitochondrial matrix. Citric acid cycle is an aerobic cellular respiration which requires oxygen for proper functioning.

Answer 12

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Answer 13

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Answer 14

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Answer 15

Ch. 16 - Prob. 1P Ch. 16 - Prob. 2P Ch. 16 - Prob. 3P Ch. 16 - Prob. 4P Ch. 16 - Prob. 5P Ch. 16 - Prob. 6P Ch. 16 - Prob. 7P Ch. 16 - Prob. 8P Ch. 16 - Prob. 9P Ch. 16 - Prob. 10P

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