EBK FOUNDATIONS IN MICROBIOLOGY: BASIC
10th Edition
ISBN: 8220103675406
Author: TALARO
Publisher: YUZU
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Chapter 1.6, Problem 16CYP
Explain the binomial system of nomenclature and give the correct order of taxa, going from most general to most specific.
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1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple different routes of administration provides greater insight than just a single route of administration alone. The following data was collected in 250 g rats following bolus iv, oral (po), and intraperitoneal (ip) administration.Using this data and set of graphs, determine:
(a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data (c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e) absolute po bioavailability, (f)Fpo absolute ip bioavailability, Fip
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2. Drug quantification from plasma is commonly performed by using techniques such as HPLC or LC/MS. However, these methods do have limitations, and investigators may choose to use a radiolabeled analog of a drug instead. Radioligands are molecules that contain radioactive isotopes, commonly 3H or 14C. This technique allows investigators to quantify drug concentration from radiation measurements. The following measurements were made in 250 g rats following oral administration of 18.2 µCi of a 14C-labeled drug of interest: Time (min) Plasma Radiation Levels (µCi/L) 0 0.0 2 9.7 4 19.2 7 25.3 9 37.8 12 39.6 14 45.8 17 48.8 20 52.0 25 56.4 30 59.2 35 60.1 40 61.1 45 62.1 50 62.8 60 63.1 70 62.1 80 60.1 90 57.3 100 55.5 110 53.7 120 52.2 150 48.0 180 45.0 240 39.0
Note that a µCi is a measure of the amount of radioactivity and hence is a measure of the amount of drug present. Given that the oral bioavailability of this drug is known to be essentially 100%, estimate the following from this…
The current nutrition labelling regulation in Hong Kong requires food manufacturer to list E+7 information on the package of pre-packaged food products. Do you think that more nutrients, such as calcium and cholesterol, shall be included?
Chapter 1 Solutions
EBK FOUNDATIONS IN MICROBIOLOGY: BASIC
Ch. 1.1 - Define microbiology and microorganisms, and...Ch. 1.1 - Name and define the primary fields included in...Ch. 1.1 - Define what is meant by the term microorganism and...Ch. 1.1 - Describe five different ways in which humans...Ch. 1.2 - Prob. 3ELOCh. 1.2 - Prob. 4ELOCh. 1.2 - Prob. 5ELOCh. 1.2 - Prob. 3CYPCh. 1.2 - Observe figure 1.3 and place the microbes pictured...Ch. 1.2 - Prob. 5CYP
Ch. 1.2 - Prob. 6CYPCh. 1.3 - Prob. 6ELOCh. 1.3 - Describe several ways the beneficial qualities of...Ch. 1.4 - Prob. 7ELOCh. 1.4 - Prob. 8ELOCh. 1.4 - Prob. 8CYPCh. 1.4 - Prob. 9CYPCh. 1.5 - Prob. 9ELOCh. 1.5 - Prob. 10ELOCh. 1.5 - Prob. 10CYPCh. 1.5 - Prob. 11CYPCh. 1.5 - Prob. 12CYPCh. 1.5 - Why was the abandonment of the spontaneous...Ch. 1.6 - Define taxonomy and its supporting terms...Ch. 1.6 - Prob. 12ELOCh. 1.6 - Describe the goals of nomenclature and how the...Ch. 1.6 - Prob. 14CYPCh. 1.6 - Prob. 15CYPCh. 1.6 - Explain the binomial system of nomenclature and...Ch. 1.6 - Explain sonic of the benefits of using scientific...Ch. 1.7 - Prob. 14ELOCh. 1.7 - Explain the concepts behind the organization of...Ch. 1.7 - Explain the bases foe classification, taxonomy,...Ch. 1.7 - Prob. 17ELOCh. 1.7 - Prob. 18CYPCh. 1.7 - Prob. 19CYPCh. 1.7 - Prob. 20CYPCh. 1.7 - Archaea are often found living in extreme...Ch. 1.7 - Compare the domain system with the five-kingdom...Ch. 1.L1 - Which of the following is not considered a...Ch. 1.L1 - An area of microbiology that is concerned with the...Ch. 1.L1 - Which process involves the deliberate alteration...Ch. 1.L1 - A prominent difference between prokaryotic and...Ch. 1.L1 - Prob. 5MCQCh. 1.L1 - Abiogenesis refers to the a. spontaneous...Ch. 1.L1 - Prob. 7MCQCh. 1.L1 - Prob. 8MCQCh. 1.L1 - Which scientist is most responsible for finally...Ch. 1.L1 - Prob. 10MCQCh. 1.L1 - Prob. 11MCQCh. 1.L1 - Prob. 12MCQCh. 1.L1 - Prob. 13MCQCh. 1.L1 - Prob. 14MCQCh. 1.L1 - Prob. 15MCQCh. 1.L1 - Prob. 16MCQCh. 1.L1 - Many of the bacteria in Lake Whillans derive...Ch. 1.L1 - Prob. 2CSRCh. 1.L1 - Prob. 3CSRCh. 1.L1 - What does it mean to say microbes are ubiquitous?Ch. 1.L1 - Prob. 2WCCh. 1.L1 - What events, discoveries, or inventions were...Ch. 1.L1 - Prob. 4WCCh. 1.L1 - Explain how microbes arc classified into groups...Ch. 1.L1 - Prob. 6WCCh. 1.L2 - What do you suppose the world would be like if...Ch. 1.L2 - How would you describe the types of scientific...Ch. 1.L2 - Give the technical name of a microbiologist who...Ch. 1.L2 - Name the six most common infectious agents on...Ch. 1.L2 - Prob. 5CTCh. 1.L2 - Prob. 6CTCh. 1.L2 - Construct the scientific name of a newly...Ch. 1.L2 - Prob. 1VC
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