Ribavirin contains a 1,2,4-triazole ring. Why the ring is aromatic is to be explained. Concept introduction: A compound to become aromatic should obey Huckel’s rule. According to Huckel’s rule, any species that is cyclic, planar and has (4n+2) delocalized Ï€ electrons will be aromatic and stable. Thus species with 2, 6, 10, 14 etc. Ï€ electrons will be aromatic and stable. To explain: Why the 1,2,4-triazole ring is aromatic.

Question

Consider the following Figure 2 and two atoms that are initially an infinite distance apart, x =00, at which point the potential energy of the system is U = 0. If they are brought together to x = x, the potential energy is related to the total force P by dU dx = P Given this, qualitatively sketch the variation of U with x. What happens at x=x? What is the significance of x = x, in terms of the potential energy? 0 P, Force 19 Attraction Total Repulsion x, Distance Figure 2. Variation with distance of the attractive, repulsive, and total forces between atoms. The slope dP/dx at the equilibrium spacing xe is proportional to the elastic modulus E; the stress σb, corresponding to the peak in total force, is the theoretical cohesive strength.

Answer 1

Question

Chapter 15.SE, Problem 38AP

Interpretation Introduction

Interpretation:

Ribavirin contains a 1,2,4-triazole ring. Why the ring is aromatic is to be explained.

Concept introduction:

A compound to become aromatic should obey Huckel’s rule. According to Huckel’s rule, any species that is cyclic, planar and has (4n+2) delocalized Ï€ electrons will be aromatic and stable. Thus species with 2, 6, 10, 14 etc. Ï€ electrons will be aromatic and stable.

To explain:

Why the 1,2,4-triazole ring is aromatic.

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