Life: The Science of Biology
11th Edition
ISBN: 9781319010164
Author: David E. Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker
Publisher: W. H. Freeman
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Chapter 15.4, Problem 2R
Summary Introduction
To review:
The process by which allele-specific oligonucleotide hybridization can be used to detect sickle-cell anemia.
Introduction:
Sickle-cell anemia is genetic disorder in which abnormal rigid, sickle-shaped hemoglobin is produced in red blood cell (RBC). Hemoglobin is responsible for caring and transmitting oxygen to the several parts of the body. Rigid sickle-shaped hemoglobin fails to transmit proper oxygen to the body parts. These result in chronic pain, swelling of hand and feet, stroke, etc.
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Life: The Science of Biology
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